Arizona Cardinals vs San Francisco 49ers Prediction, 10/6/2024 NFL Picks, Best Bets & Odds Week 5

Game: Arizona Cardinals at San Francisco 49ers

Date: Sunday, October 6, 2024

Location: Levi's Stadium in Santa Clara, CA

TV: Fox

Odds/Point Spread: 49ers (-7.0)

Total/Over-Under: 49.5

Levi's Stadium is the site where the San Francisco 49ers (2-2) will attempt to defeat the Arizona Cardinals (1-3) on Sunday. San Francisco opens this game as 7.0-point favorites. The total is 49.5.

The Arizona Cardinals head into this matchup 1-3 for this season. The last time they took the field, the Cardinals faced off with the Washington Commanders and walked away from this one with a loss by a score of 42-14. Kyler Murray finished 16/22 with 142 yds passing and 1 touchdown. He had a QB rating of 104.7 and walked away from the game with no picks. James Conner was the rushing leader for the Cardinals with 18 carries for 104 yards (5.8 yds per carry). Marvin Harrison Jr. averaged 9.0 yards per reception by accumulating 45 yds on 5 catches. The Arizona Cardinals ran the rock 32 different times and accrued 181 yards, earning them an average of 5.7 yards per attempt. In all, they had 54 plays which totaled 296 yards. Arizona gave up 26 completions on 30 attempts for 233 yards, and a completion percentage of 86.7%. On the ground, the Cardinals conceded 216 yds on 37 attempts, which calculates to 5.8 yds per run surrendered.

Regarding getting in the endzone, the Arizona Cardinals have an average of 24.0 points per game. As a team they're averaging 153.3 yards in the run game ranking them 5th in the National Football League. The Cardinals have racked up 1,332 total yards for this campaign. Arizona has earned 34 1st downs as a team, and they have been called for 18 infractions for 195 yds. They have surrendered the football 4 times (1 pick and 3 fumbles lost). In terms of distribution of touchdowns, Arizona has amassed 6 touchdowns via the pass and 3 rushing touchdowns.

When it comes to yards via the pass, the Cardinals have surrendered 833 yards which has them ranked 18th in the league. They are allowing 208.3 yards per contest via the pass as well as allowing a completion percentage of 78.6%. They have yielded 5 touchdowns through the air as well as 8 touchdowns on the ground. During the season, they have given up 354.8 yards/outing which has them ranked 25th in the NFL. Opposing teams are running for an average of 4.4 yards per running attempt and 146.5 yards on the ground per game for the season. The Cardinals are sitting in 29th in the league in terms of the opposition scoring, allowing 26.5 PPG. Over the course of this year, they have allowed 586 yards via the ground game in 4 outings.

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The 49ers come into this game with a record of 2-2 for this season. The last time they stepped on the gridiron, the 49ers walked away with a victory by a final of 30-13 when they played the New England Patriots. Jordan Mason carried the rock 24 times for 123 yds, ending the game with 5.1 yds per attempt for San Francisco. Jauan Jennings was the best receiver for the 49ers, snagging 3 throws for 88 yds (29.3 yds per catch). Brock Purdy (1 touchdown) walked away from the contest with 288 yds on 15/27 through the air while his quarterback rate was 89.7. He tossed 1 interception and his Y/A was 10.7 yards. San Francisco relinquished 24 running attempts for 73 yds (3.0 yards per rush). The 49ers secondary conceded a completion rate of 59.4%, surrendering 143 yds on 19 out of 32 through the air. The 49ers finished the game with 431 yards and they ran 59 plays (7.3 yards per play). San Francisco ran for 4.6 yards per tote, totaling 148 yds on 32 carries.

In terms of putting points on the board, the 49ers are 8th out of all teams in the league with an average of 25.8 PPG. During this campaign to this point, the 49ers have compiled 1,086 passing yards as well as holding an average of 271.5 passing yards per game, which has them sitting 2nd in football. They are averaging 141.8 yards per game on the ground and have run for 567 yards overall. The San Francisco 49ers are averaging 413.3 yards per game ranking them 2nd out of all teams in the NFL. The San Francisco offense has compiled 224 penalty yds on 21 infractions, which has them sitting 24th in the league in terms of hurting your team.

The 49ers are surrendering 20.5 PPG, which has them ranked 10th of all teams in the league. They have allowed 6 touchdowns via the pass as well as 199.0 yards per outing, which puts them in 15th in the league. San Francisco has surrendered a total of 385 rushing yards (96.3 yards per outing) and 3 touchdowns on the ground this season. The 49ers defense has been on the field for 220 plays, which has them sitting 3rd in the league. They have tallied 7 takeaways (4 fumbles recovered and 3 picks) so far this year.

Who will win tonight's Cardinals/49ers NFL game against the spread?

Tony's Pick: Take the 49ers -7.0

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