Indianapolis Colts vs Buffalo Bills Prediction, 11/21/2021 NFL Picks, Best Bets and Tips Week 11

Game: Indianapolis Colts vs Buffalo Bills

Date: Sunday, November 21, 2021

Location: Highmark Stadium in Orchard Park, NY

TV: CBS

Odds/Point Spread: Bills (-7)

Total/Over-Under: 50

The Indianapolis Colts (5-5) are on their way to Highmark Stadium on Sunday where they will attempt to defeat the Buffalo Bills (6-3). Buffalo opens as 7-point favorites from Vegas oddsmakers. The total is set at 50.

The Indianapolis Colts head into this matchup 5-5 for this year. In their last contest, the Colts stepped onto the field against the Jaguars and earned the victory with a final of 23-17. Carson Wentz connected on 22/34 with 180 yards passing. He had a quarterback rating of 78.1 and finished the game without throwing an interception. Jonathan Taylor was the best rusher for the Colts with 21 attempts for 116 yds (5.5 yards per attempt). Michael Pittman Jr. held an average of 14.2 yds per catch by notching 71 yds on 5 catches. The Indianapolis Colts ran the football 27 different times and accounted for 127 yards, which came out to an average of 4.7 yards per tote. Overall, they tallied 62 plays which totaled 295 yds. Indianapolis surrendered 16 completions on 35 tries for 152 yards, and a completion rate of 45.7%. In the running game, the Colts conceded 179 yards on 24 tries, which calculates to 7.5 yards per run allowed.

The Colts have tallied 3,634 yards in total over the course of this year. Indianapolis has accumulated 110 1st downs as a unit, and they have been called for 48 penalties for 437 yds. In terms of scoring touchdowns, Indianapolis has totaled 17 passing touchdowns and 12 rushing touchdowns. They have turned the football over 10 different times (4 picks and 6 fumbles). As a team they hold an average of 136.3 yards in the run game which has them sitting 6th in the National Football League. In terms of scoring, the Indianapolis Colts have an average of 26.8 points per game.

Concerning yards through the air, the Colts have conceded 2,499 yards which puts them in 26th in the NFL. They have given up 249.9 yards per game via the pass and giving up a completion percentage of 66.9%. For the year, they are surrendering 363.6 yards per game which ranks them 19th in the National Football League. They have surrendered 23 touchdowns via the pass in addition to 4 touchdowns pounding the rock. They are allowing 4.3 yards per rush on the ground and 113.7 rushing yards per game this season. Over the course of this season, they have conceded 1,137 rushing yards through 10 games. The Colts rank 13th in the league in terms of team defense, conceding 23.0 points per game.

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The Bills head into this game 6-3 for this season. When they last stepped on the field, the Bills got the victory with a final of 45-17 against the Jets. Josh Allen (2 touchdowns) walked away from the contest with 366 yds on 21/28 through the air while his quarterback rating was 125.6. He threw 1 pick and his average yards per pass attempt was 13.07 yards. Stefon Diggs was featured in the passing game for the Bills, grabbing 8 footballs for 162 yds (20.3 yds per catch). Zack Moss ran the ball 7 times for 27 yards, finishing the contest with 3.9 yards per carry for Buffalo. The Bills finished the game with a total of 489 yards and they ran 54 plays (9.1 yards per play). Buffalo ran for 5.8 yards per tote, finishing the contest with 139 yards on 24 attempts. Buffalo allowed 22 rush attempts for 70 yards (3.2 yards per rush). The Bills passing defense conceded a completion rate of 57.4%, relinquishing 296 yds on 27 out of 47 passing.

Regarding how much they score, the Bills rank 2nd in the NFL averaging 31.1 points per outing. For the year so far, the Bills have a total of 2,513 yards via the pass in addition to an average of 279.2 throwing yards per game, which ranks 6th out of all NFL teams. They maintain an average of 121.9 yards per game on the ground and have toted the ball for 1,097 yards for this season. The Buffalo Bills are averaging 401.1 yards per contest which has them ranked 5th in the league. The Buffalo offense has racked up 605 penalty yds on 68 infractions, which is good for 6th in the league in terms of hurting your team. They have thrown 6 picks while letting opponents recover 4 fumbles and they have been able to tally 132 1st downs.

Buffalo has surrendered a total of 755 yards on the ground (83.9 yards per game) as well as 7 touchdowns via the rush this season. They have given up 6 touchdowns through the air as well as 190.2 yards per contest, ranking them 2nd in the NFL. They have tallied 24 takeaways (9 fumbles and 15 interceptions) on the campaign. This season, they have surrendered 135 points in total. The Bills defense has been on the field for 538 plays, which is good for 1st in the NFL. The Bills are conceding 15.0 points per contest, ranking them 1st of all teams in the NFL.

Who will win tonight's Colts/Bills NFL game against the spread?

Guy's Pick: Take the Bills -7

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