Toronto Blue Jays vs Houston Astros Prediction, 4/22/2025 MLB Picks, Best Bets & Odds

Game: Toronto Blue Jays vs Houston Astros

Date: Tuesday, April 22, 2025

Location: Daikin Park in Houston, TX

TV: Space City Home Network

Odds/Point Spread: Toronto (-275) Houston (+220)

The Houston Astros (10-11) host the Toronto Blue Jays (12-10) at Daikin Park on Tuesday. The moneyline on this game has the Blue Jays at -275 and the Astros are opening at +220. The total comes in at 9. The starting pitchers are Chris Bassitt and Ronel Blanco.

Toronto is slugging .368 and have been called out on strikes 154 times, while drawing a walk on 75 occasions. They have 81 runs batted in as well as 192 hits so far this season, while their team batting average comes in at .259. The Blue Jays have recorded 43 two-baggers as a squad and have hit 12 balls out of the park. They have 86 runs and have an on-base percentage of .333. As a unit, the Toronto Blue Jays are notching 3.9 runs per contest, which ranks them 22nd in the league.

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Their K/BB ratio is 3.23 and their pitching staff holds a collective WHIP of 1.11. Blue Jays pitchers have surrendered 31 home runs in addition to 89 runs in total (10th in the league). Toronto has surrendered 157 base hits (7.0 per 9 innings) in addition to 80 earned runs. The Blue Jays have a team earned run average of 3.58 on the year (8th in MLB), and the staff has rung up 213 batters. Their pitching staff has walked 66 opposing batters and their FIP is 4.07 as a unit for the season.

The Blue Jays have sent 79 relievers to the hill for the year. The relief pitchers have inherited 31 base runners so far this season and 22.6% of those players ended up crossing the plate. They have compiled 7 saves on the season and have missed out on 4 out of their 11 save opportunities. The Blue Jays relief pitchers have recorded a save rate of 63.6% and have come into the game in 28 save situations. The relief pitchers have a total of 17 holds this season (10th in MLB). Blue Jays bullpen pitchers have stepped onto the hill with runners on base 26 times and also have had 20 appearances in high leverage situations.

The Toronto Blue Jays are sitting with 604 putouts for the season, in addition to 170 assists and 12 errors. Their fielding percentage sits at .985 which has them ranked 18th in MLB, and they have turned 16 double plays. The Blue Jays have turned 73.1% of balls in play into outs in their 1,812 innings on the diamond, which ranks them 5th in the majors.

Bassitt has pitched in 1,131 frames and has accumulated 1,056 strikeouts during his MLB career. Bassitt (74-56 career record) has a FIP of 3.48 and he has gone up against 4,767 hitters during his time in the majors. His ERA is 3.53 (444 earned runs allowed) and he has a WHIP of 1.231. He has conceded 1,030 base knocks (8.2 hits per nine innings) and has 362 free passes.

The Astros have a SLG% of .331 and they average 3.67 runs per game (24th in the league). They have put up 22 two-baggers, while taking a walk 71 times and scoring 77 runs. Houston has accumulated 17 home runs on the campaign to go along with 70 RBIs. They have struck out on 174 occasions (21st in baseball) and are sitting with 153 hits. The Houston Astros are sitting with a team on-base percentage of .299 in addition to a batting average of .222 so far this season.

The Houston pitching staff have conceded 79 runs for the year while having a team ERA of 3.63 (76 earned runs surrendered). They have allowed 20 homers and they allow 3.78 runs per 9 innings (4th in MLB). The Astros have a team WHIP of 1.158 and have a FIP of 3.49 as a pitching staff this year. Their K/BB ratio sits at 9.40 (198 strikeouts against 66 walks). They are sitting at 5th in the league as a pitching staff in total hits given up with 152.

Houston bullpen pitchers hold an inherited score rate of 33.3% out of 24 inherited runners. Their bullpen pitchers have stepped onto the hill 22 times in high leverage situations and on 17 occasions with runners on. Sitting with 26 save situations, the Astros have compiled 16 holds and also 3 blown saves. They rank 9th in baseball with a save percentage of 70.0%, and they have sent 70 relievers to the mound on the year. Houston has called on bullpen pitchers to enter the game in 10 save opportunities and they have recorded 7 saves.

Out of their 1,698 innings on the diamond, the Astros have a defensive efficiency of 71.6% (9th in baseball). The Houston Astros have turned 13 double plays and own a fielding percentage of .986 (14th in the majors). The Astros have recorded 164 assists, 10 errors and have a tally of 566 putouts so far this season.

Blanco (16-9 mark in his career) has earned a 3.54 earned run average while conceding 7.0 hits per 9 innings. He has a K/BB ratio of 2.20 and he has faced 1,010 opposing batters so far in his career. He has allowed a total of 95 earned runs while earning a WHIP of 1.239 and having a FIP of 3.5. In his career, Blanco has surrendered 189 hits while tallying 242 K's in 241 innings.

Who will win tonight's MLB game against the spread or moneyline?

Guy Bruhn's Pick: Take Houston (+220)

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