Tampa Bay Rays vs San Diego Padres Prediction, 4/27/2025 MLB Picks, Best Bets & Odds

Game: Tampa Bay Rays vs San Diego Padres

Date: Sunday, April 27, 2025

Location: Petco Park in San Diego, CA

TV: Padres.TV

Odds/Point Spread: Tampa Bay (+162) San Diego (-196)

Petco Park is the location where the San Diego Padres (17-8) will play the Tampa Bay Rays (11-14) on Sunday. The moneyline on this game has the Rays at +162 and the Padres open at -196. The betting total comes in at 8. The pitchers taking the mound are Zack Littell and Randy Vasquez.

The Rays have recorded 44 doubles as a unit and have smacked 23 baseballs out of the stadium. Tampa Bay is slugging .397 and have struck out 206 times, while drawing a walk on 80 occasions. As a squad, the Tampa Bay Rays are compiling 4.4 runs per contest, which puts them at 15th in the league. They have compiled 105 runs batted in and 212 base knocks this year, while their batting average is .255. They have accounted for 109 runs scored while holding a team on-base percentage of .321.

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They have a K/BB ratio of 3.15 and their pitching staff has a collective WHIP of 1.18. Rays pitchers have surrendered 39 home runs in addition to 101 runs in total (10th in baseball). Tampa Bay has given up 194 base hits (7.8 per 9 innings) in addition to 94 earned runs. The Rays have an ERA of 3.75 this season (9th in MLB), and their staff has rung up 224 hitters. They have walked 71 hitters and their FIP is 4.37 as a squad on the campaign.

The Rays have sent 79 relief pitchers to the mound on the season. The relievers have inherited 12 base runners over the course of the season with 50.0% of those runners ended up crossing the plate. They have accumulated 5 saves for the season and have blown 3 out of their 8 save chances. The Rays bullpen have recorded a save rate of 62.5% and have entered the game in 16 save situations. The relievers have notched 8 holds this season (28th in the league). Rays relief pitchers have gone to the mound with runners on 9 times in addition to having 20 appearances in high leverage situations.

The Tampa Bay Rays are sitting with 677 putouts on the campaign, in addition to 226 assists and 11 errors. Their fielding percentage is at .988 which is 12th in MLB, and have a total of 25 double plays. The Rays have converted 72.2% of balls hit into play into outs out of 2,031 innings, which has them sitting 6th in MLB.

Littell has taken the mound for 445 innings and has totaled 387 strikeouts in his career. Littell (24-26 career win-loss record) sits with a FIP of 3.94 while he has gone up against 1,874 opposing hitters during his time in the major leagues. His ERA is 4.00 (198 ER's allowed) and his career WHIP is 1.263. He has surrendered 452 hits (9.1 hits per 9 innings) and has 110 walks.

The San Diego Padres are sitting with an on-base percentage of .333 in addition to a batting average of .263 this season. They have been called out on strikes on 169 occasions (30th in MLB) and have 216 base hits. San Diego is sitting with 24 long balls this year to go along with 94 runs batted in. The Padres have a team slugging % of .401 and they score 4.12 runs per game (19th in the league). They have 39 two-baggers, while getting a free base 84 times as well as scoring 103 runs.

The Padres hold a team WHIP of 1.123 and have a FIP of 3.42 as a staff this year. Their K/BB ratio comes in at 8.60 (209 strikeouts vs 79 bases on balls). They are sitting at 3rd in the league as a staff in total hits allowed with 167. They have conceded 19 homers and they concede 3.04 runs per 9 innings (2nd in baseball). The San Diego pitching staff have conceded 74 runs for the season while holding an ERA of 2.92 (71 earned runs yielded).

Sitting with 31 save situations, the Padres have amassed 19 holds in addition to 1 blown save. San Diego has called on relievers to step onto the mound in 12 save chances and they have walked away with 11 saves. Their relievers have stepped onto the hill 32 times in high leverage situations and on 18 occasions with base runners. San Diego bullpen pitchers have an inherited score percentage of 30.8% of 26 inherited runners. They rank 1st in the league with a save percentage of 91.7%, and they have dispatched 80 relief pitchers to the mound this season.

In 1,971 innings played, the Padres have earned a defensive efficiency of 73.4% (4th in pro baseball). The San Diego Padres have turned 17 double plays and own a fielding percentage of .988 (9th in professional baseball). The Padres have recorded 179 assists, 10 errors and have amassed 657 putouts this season.

In his career, Vasquez has surrendered 168 base hits while he has accumulated 104 strikeouts in 157 innings pitched. He has surrendered 75 earned runs while earning a WHIP of 1.474 and a FIP of 4.2. He has a strikeout to walk ratio of 1.63 and he has faced 698 batters so far in his MLB career. Vasquez (7-11 win-loss mark in his career) has earned a 4.29 earned run average and has given up 9.6 hits per nine innings.

Who will win tonight's MLB game against the spread or moneyline?

Tony Sink's Pick: Take San Diego (-196)

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