Tampa Bay Rays vs San Diego Padres Prediction, 4/26/2025 MLB Picks, Best Bets & Odds

Game: Tampa Bay Rays vs San Diego Padres

Date: Saturday, April 26, 2025

Location: Petco Park in San Diego, CA

TV: Padres.TV

Odds/Point Spread: Tampa Bay (+150) San Diego (-182)

The Tampa Bay Rays (10-14) are en route to Petco Park on Saturday where they will attempt to beat the San Diego Padres (17-8). The moneyline on this game has the Rays at +150 while the Padres are sitting at -182. The total is 8. The expected starting pitchers are Ryan Pepiot and Dylan Cease.

As a unit, the Tampa Bay Rays are scoring 4.3 runs per game, which has them at 17th in MLB. They have accounted for 102 runs while holding a team on-base percentage of .323. The Rays have accrued 40 two-baggers as a unit and have knocked 22 balls out of the park. They have 99 RBI's and 203 hits on the campaign, and their team batting average sits at .256. Tampa Bay owns a slugging percentage of .398 and have struck out 190 times, while taking a walk on 77 occasions.

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Their strikeout to walk ratio sits at 3.19 and their pitching staff has a collective WHIP of 1.19. Rays pitchers have given up 38 home runs and also 97 runs (9th in the league). Tampa Bay has yielded 188 hits (7.9 per 9 innings) as well as 90 earned runs. The Rays hold a team ERA of 3.76 over the course of the season (9th in the league), and they have struck out 217 hitters. Their pitching staff has walked 68 hitters and their FIP sits at 4.39 as a unit so far this season.

The Rays have sent 75 relief pitchers to the mound so far this year. The bullpen pitchers have inherited 12 runners on the campaign with 50.0% of those players ended up crossing the plate. They have accumulated 4 saves for the season and have not converted 3 of their 7 chances to save the game. The Rays relief pitchers have a save percentage of 57.1% and have stepped onto the mound in 15 save situations. The relievers have tallied 8 holds over the course of the season (28th in MLB). Rays relief pitchers have gone to the mound with runners on base 8 times as well as having 18 appearances in high leverage situations.

The Tampa Bay Rays have accounted for 647 putouts this year, as well as 215 assists and 11 errors. Their fielding percentage is holding at .987 which is 13th in the majors, and they have turned 23 double plays. The Rays have converted 71.8% of baseballs in play into outs out of their 1,941 innings, which ranks them 8th in professional baseball.

Pepiot has taken the ball for 236 innings and is sitting with 253 strikeouts in his career. His earned run average is 3.47 (91 ER's allowed) and his career WHIP is 1.173. He has surrendered 187 base hits (7.1 hits per 9 innings) and has 90 walks. Pepiot (14-12 win-loss mark in his career) is the owner of a FIP of 3.42 while he has faced 985 batters in the major leagues.

San Diego has a total of 24 home runs for the year as well as 94 RBIs. They have tallied 39 two-baggers, while walking 84 times as well as scoring 103 runs. The San Diego Padres have an on-base percentage of .333 in addition to a batting average of .263 on the season. The Padres hold a slugging percentage of .401 and they earn 4.12 runs per contest (19th in the league). They have been called out on strikes on 169 occasions (30th in the league) and have notched a total of 216 base hits.

The Padres have a team WHIP of 1.123 and have a FIP of 3.42 as a team for the season. Their strikeout to walk ratio sits at 8.60 (209 strikeouts against 79 free passes). They are currently ranked 3rd in the league as a pitching staff in total hits given up with 167. They have relinquished 19 dingers and they surrender 3.04 runs per 9 innings (2nd in baseball). The San Diego pitching staff have conceded 74 runs this season while holding an ERA of 2.92 (71 earned runs surrendered).

San Diego bullpen pitchers have an inherited score percentage of 30.8% out of their 26 inherited base runners. Their relief pitchers have come in 32 times in high leverage situations and also on 18 occasions with base runners. Sitting with 31 save situations, the Padres have compiled 19 holds and also 1 blown save. They rank 1st in baseball with a save percentage of 91.7%, and they have dispatched 80 bullpen pitchers to the mound on the campaign. San Diego has called on relievers to step onto the mound in 12 save chances and they have converted 11 saves.

In 1,971 innings on the diamond, the Padres have a defensive efficiency of 73.4% (4th in baseball). The San Diego Padres have turned 17 double plays and have accounted for a fielding rate of .988 (7th in the majors). The Padres have accrued 179 assists, 10 errors and have a tally of 657 putouts for the season.

Cease (58-47 career mark) holds a 3.82 ERA and has given up 7.6 hits per 9 innings. He has a K/BB ratio of 2.85 and he has gone up against 3,695 opposing hitters so far in his MLB career. He has conceded a total of 370 ER's while earning a WHIP of 1.260 and having a FIP of 3.8. So far in his pro baseball career, Cease has allowed 732 base knocks while he has earned 1,046 strikeouts in 872 innings.

Who will win tonight's MLB game against the spread or moneyline?

Tony Sink's Pick: Take San Diego (-182)

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