St. Louis Cardinals vs Cincinnati Reds Prediction, 4/29/2025 MLB Picks, Best Bets & Odds

Game: St. Louis Cardinals vs Cincinnati Reds

Date: Tuesday, April 29, 2025

Location: Great American Ball Park in Cincinnati, OH

TV: FanDuel Sports Network Ohio

Odds/Point Spread: St. Louis (+125) Cincinnati (-145)

Great American Ball Park is the location where the Cincinnati Reds (15-13) will meet the St. Louis Cardinals (12-16) on Tuesday. The moneyline on this game has the Cardinals at +125 and the Reds are opening at -145. The over/under has been set at 8.5. The pitchers taking the mound are Miles Mikolas and Brady Singer.

St. Louis owns a slugging percentage of .401 and have been rung up 221 times, while drawing a walk on 100 occasions. They have 123 RBI's and 259 base knocks for the season, while their average at the plate comes in at .265. The Cardinals have recorded 58 two-baggers as a squad and have hit 24 balls out of the park. They are sitting with 130 runs scored while having a team OBP of .336. As a team, the St. Louis Cardinals are putting up 4.6 runs per game, which ranks them 10th in baseball.

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The Cardinals have compiled a team ERA of 4.36 on the campaign (21st in baseball), and their staff has rung up 193 batters. Cardinals pitchers have conceded 23 home runs in addition to 132 runs (22nd in the league). They have walked 85 players from the other team and their FIP is 3.81 as a team on the campaign. St. Louis has conceded 227 hits (8.2 per 9 innings) as well as 121 earned runs. Their strikeout to walk ratio is 2.27 and the pitching staff has a team WHIP of 1.25.

The Cardinals relievers have compiled a save rate of 46.2% and have entered the game in 32 save situations. The relief pitchers have inherited 34 base runners so far this year and 47.1% of them earned a run for their team. Cardinals relief pitchers have entered the game with opponents on base 31 times as well as having 41 appearances in high leverage situations. The Cardinals have sent 93 relievers to the hill on the campaign. The bullpen have a total of 19 holds this year (12th in the league). They have compiled 6 saves this year and have not converted 7 out of their 13 save chances.

The Cardinals have transformed 71.5% of balls hit into play into outs in their 2,247 innings on the diamond, which has them ranked 8th in pro baseball. The St. Louis Cardinals have earned a total of 749 putouts at this point in the season, in addition to 280 assists and 11 errors. Their fielding rate is currently at .989 which ranks 3rd in baseball, and have a total of 17 double plays.

Mikolas has taken the ball for 1,119 innings and is sitting with 808 punch outs during his pro baseball career. Mikolas (64-66 career mark) is the owner of a FIP of 4.13 and he has gone up against 4,655 batters during his time in the major leagues. His earned run average is 4.19 (521 earned runs allowed) and his WHIP is 1.209. He has surrendered 1,135 hits (9.1 hits per nine innings) with 218 free passes.

Cincinnati has recorded 32 long balls this season as well as 144 runs batted in. They have put up 45 doubles, while taking a walk 104 times and scoring 150 runs. The Cincinnati Reds are sitting with an OBP of .333 and a team batting average of .254 over the course of the season. The Reds have a SLG% of .404 and they have an average of 5.36 runs per outing (4th in the league). They have been called out on strikes on 243 occasions (10th in MLB) and have earned 242 base hits.

The Cincinnati pitching staff have relinquished 109 runs this season while having a team ERA of 3.46 (95 earned runs relinquished). They have given up 36 homers and they concede 3.97 runs per 9 innings (9th in MLB). The Reds hold a team WHIP of 1.101 in addition to having a FIP of 4.18 as a staff so far this year. Their strikeout to walk ratio is 8.30 (228 strikeouts vs 81 free passes). They come in at 3rd in the league as a staff in total hits surrendered with 191.

With 37 save situations, the Reds have accrued 23 holds in addition to 4 blown saves. Cincinnati has had relief pitchers step onto the hill in 13 save chances and they have walked away with 9 saves. Their relief pitchers have taken the field 28 times in high leverage situations and also on 22 occasions with runners on. Cincinnati relief pitchers hold an inherited score rate of 20.6% out of 34 inherited runners. They rank 12th in MLB with a save rate of 69.2%, and they have dispatched 92 relief pitchers onto the diamond for the year.

Out of their 2,226 innings on the field, the Reds are sitting with a defensive efficiency of 74.9% (1st in the majors). The Cincinnati Reds have gotten 10 double plays and have notched a fielding percentage of .982 (21st in professional baseball). The Reds have accrued 196 assists, 17 errors and are sitting with 742 putouts on the campaign.

Singer (40-44 record in his career) has a 4.26 earned run average and has allowed 9.1 hits per 9 innings. He has a K/BB ratio of 3.04 and he has faced 3,046 opposing batters in his career. He has given up a total of 337 earned runs while earning a WHIP of 1.320 and being the owner of a FIP of 4.2. In his pro baseball career, Singer has given up 717 hits while he has tallied 677 K's in 712 innings pitched.

Who will win tonight's MLB game against the spread or moneyline?

Tony Sink's Pick: Take St. Louis (+125)

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