St. Louis Cardinals vs Boston Red Sox Prediction, 4/5/2025 MLB Picks, Best Bets & Odds
Game: St. Louis Cardinals vs Boston Red Sox
Date: Saturday, April 5, 2025
Location: Fenway Park in Boston, MA
TV: NESN
Odds/Point Spread: St. Louis (-144) Boston (+120)
The St. Louis Cardinals (4-2) are traveling to Fenway Park on Saturday where they will meet the Boston Red Sox (2-4). The moneyline on this matchup has the Cardinals at -144 and the Red Sox are coming in at +120. The over/under comes in at 9. The pitchers taking the mound are Andre Pallante and Richard Fitts.


As a unit, the St. Louis Cardinals are compiling 7.0 runs per game, which ranks them 2nd in MLB. They have earned a total of 42 runs scored and have an OBP of .381. The Cardinals have recorded 10 two-baggers as a unit and have smacked 11 baseballs out of the park. They have accumulated 40 RBI's in addition to 64 hits for the season, while their team batting average is at .298. St. Louis has a slugging rate of .498 and have been called out on strikes 46 times, while being walked on 28 occasions.
Get all of our MLB Picks Today
The Cardinals hold a team ERA of 3.47 for the season (13th in baseball), and they have struck out 46 batters. Cardinals pitchers have surrendered 4 home runs and 25 total runs (14th in baseball). Their pitching staff has walked 13 players from the other team and their FIP is 2.92 as a squad this year. St. Louis has given up 36 hits (5.7 per 9 innings) and 22 earned runs. They have earned a strikeout to walk ratio of 3.54 and their pitching staff holds a collective WHIP of 0.86.
The Cardinals have sent 21 relievers to the mound on the campaign. The relievers have inherited 5 runners on the campaign with 40.0% of them ended up scoring. They have compiled 2 saves for the season and have missed out on 1 out of their 3 chances to save the game. The Cardinals relief pitchers have compiled a save rate of 66.7% and stepped onto the hill in 10 save situations. The relief pitchers have a total of 7 holds for the year (7th in the league). Cardinals bullpen pitchers have entered the game with runners on 6 times and also have had 14 appearances in high leverage situations.
The St. Louis Cardinals have 171 putouts for the season, in addition to 68 assists and 1 error. Their fielding percentage is currently at .996 which ranks 4th in professional baseball, and have accumulated 5 double plays. The Cardinals have turned 78.5% of balls in play into outs out of 513 innings on the diamond, ranking them 3rd in baseball.
Pallante has taken the hill for 302 frames and has totaled 213 punch outs in his career. His earned run average is 3.78 (127 earned runs allowed) and he has a career WHIP of 1.400. He has surrendered 303 base knocks (9.0 hits per nine innings) and has 120 free passes. Pallante (19-14 career win-loss record) holds a FIP of 3.73 while he has gone up against 1,289 hitters during his time in the majors.
The Boston Red Sox are sitting with a team on-base percentage of .300 as well as a batting average of .217 on the season. They have been rung up on 64 occasions (8th in the league) and have earned 44 base hits. Boston has 4 long balls for the season as well as 18 runs batted in. The Red Sox hold a slugging % of .330 and they have an average of 3.17 runs per contest (24th in MLB). They have hit 9 two-baggers, while getting a free base 23 times and scoring 19 runs.
The Red Sox hold a team WHIP of 1.180 and are the owners of a FIP of 3.47 as a squad on the year. They come in at 15th in the league as a pitching staff in total hits surrendered with 48. The Boston pitching staff have given up 21 runs this year while holding a team ERA of 3.78 (21 earned runs surrendered). Their K/BB ratio comes in at 6.50 (36 strikeouts against 11 free passes). They have surrendered 5 HR's and they allow 3.78 runs per 9 innings (11th in the league).
Boston has called on bullpen pitchers to take the mound in 2 save chances and they have walked away with 2 saves. They rank 2nd in MLB holding a save percentage of 100.0%, and they have dispatched 15 relievers to the hill over the course of the season. Their bullpen pitchers have come in 1 time in high leverage situations and also on 3 occasions with base runners. Boston bullpen pitchers have an inherited score rate of 66.7% out of 6 inherited runners. With 2 save situations, the Red Sox have earned 0 holds in addition to 0 blown saves.
The Boston Red Sox have gotten 9 double plays and have a fielding percentage of .986 (18th in baseball). The Red Sox have accrued 54 assists, 3 errors and have a total of 150 putouts this year. In their 450 innings on the diamond, the Red Sox hold a defensive efficiency of 69.3% (23rd in professional baseball).
Fitts (0-2 record in his career) is the owner of a 2.40 earned run average and has surrendered 8.6 hits per 9 innings. His strikeout to walk ratio is 1.86 and he has faced 109 hitters during his MLB career. He has given up 7 earned runs while earning a WHIP of 1.221 and a FIP of 2.4. So far in his pro baseball career, Fitts has surrendered 25 hits while he has accumulated 13 punch outs in 26 frames.
Who will win tonight's MLB game against the spread or moneyline?
Guy Bruhn's Pick: Take St. Louis (-144)
Get $60 worth of FREE premium member picks. No Obligation. No Salesman. No Credit Card. Fast Sign up with Instant Access Click Here
Get all of Today's Free MLB Picks
Get all of Today's Expert MLB Picks
Additional Resources:
Boston Red Sox - Twitter
St. Louis Cardinals - Twitter