St. Louis Cardinals vs Boston Red Sox Prediction, 4/4/2025 MLB Picks, Best Bets & Odds
Game: St. Louis Cardinals vs Boston Red Sox
Date: Friday, April 4, 2025
Location: Fenway Park in Boston, MA
TV: NESN
Odds/Point Spread: St. Louis (-152) Boston (+126)
Fenway Park is where the Boston Red Sox (2-4) will take on the St. Louis Cardinals (4-2) on Friday. The moneyline on this contest has St. Louis at -152 while Boston is sitting at +126. The total has been set at 8. The expected starting pitchers are Erick Fedde and Walker Buehler.


The Cardinals have accounted for 10 doubles as a unit and have hit 11 balls out of the park. St. Louis owns a slugging percentage of .498 and have been called out on strikes 46 times, while being walked on 28 occasions. As a unit, the St. Louis Cardinals are scoring 7.0 runs per game, which has them at 2nd in MLB. They have 40 runs batted in and 64 hits for the year, and their team batting average is at .298. They are sitting with 42 runs scored and have an OBP of .381.
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The Cardinals have an ERA of 3.47 on the campaign (13th in the league), and the staff has struck out 46 batters. Cardinals pitchers have allowed 4 long balls and also 25 runs (14th in MLB). They have walked 13 batters and their FIP is 2.92 as a squad for the season. St. Louis has surrendered 36 base knocks (5.7 per 9 innings) and also 22 earned runs. They have a strikeout to walk ratio of 3.54 and the pitching staff has a team WHIP of 0.86.
The Cardinals have dispatched 21 relievers to the hill on the year. The bullpen pitchers have inherited 5 runners on the season with 40.0% of those players ended up scoring. They have compiled 2 saves for the year and have missed out on 1 out of their 3 chances to get a save. The Cardinals relievers have accumulated a save rate of 66.7% and has come into the game in 10 save situations. The relievers have a total of 7 holds on the year (7th in the league). Cardinals relief pitchers have entered the contest with runners on 6 times and also have had 14 appearances in high leverage situations.
The St. Louis Cardinals are sitting with 171 putouts thus far, as well as 68 assists and 1 error. Their fielding rate is at .996 which puts them in 4th in pro baseball, and have accumulated 5 double plays. The Cardinals have transformed 78.5% of balls hit into play into outs out of their 513 innings on the diamond, ranking them 3rd in baseball.
Fedde has taken the ball for 637 innings and has 508 K's during his MLB career. Fedde (31-42 career mark) has a FIP of 4.72 while he has faced 2,758 opposing batters in the major leagues. His earned run average is 4.79 (339 ER's allowed) and his career WHIP is 1.412. He has surrendered 657 base knocks (9.3 hits per nine innings) with 243 free passes.
Boston is sitting with 4 long balls for the season as well as 18 runs batted in. They have hit 9 doubles, while taking a walk 23 times and recording 19 runs. The Boston Red Sox have an on-base percentage of .300 as well as a team batting average of .217 for the year. The Red Sox hold a team slugging percentage of .330 and they are scoring 3.17 runs per contest (24th in baseball). They have been called out on strikes on 64 occasions (8th in baseball) and have 44 hits.
The Boston pitching staff have conceded 21 runs on the season while having a team ERA of 3.78 (21 earned runs conceded). They have conceded 5 homers and they allow 3.78 runs per 9 innings (11th in baseball). The Red Sox are sitting with a team WHIP of 1.180 and are the owners of a FIP of 3.47 as a squad this season. They have earned a K/BB ratio of 6.50 (36 strikeouts vs 11 free passes). They are currently ranked 15th in the league as a staff in total hits conceded with 48.
Boston has called on bullpen pitchers to step onto the hill in 2 save chances and they have come away with 2 saves. They rank 2nd in MLB with a save rate of 100.0%, and they have dispatched 15 relief pitchers onto the diamond for the year. Their relief pitchers have stepped onto the mound 1 time in high leverage situations and on 3 occasions with runners on base. Boston bullpen pitchers have an inherited score percentage of 66.7% out of 6 inherited base runners. With 2 save situations, the Red Sox have 0 holds and also 0 blown saves.
The Boston Red Sox have gotten 9 double plays and hold a fielding percentage of .986 (18th in pro baseball). The Red Sox have recorded 54 assists, 3 errors and have accumulated 150 putouts for the year. In 450 innings on the field, the Red Sox are sitting with a defensive efficiency of 69.3% (23rd in the majors).
During his career, Buehler has conceded 595 hits while he has earned 757 punch outs in 717 innings pitched. Buehler (47-23 career mark) has a 3.30 earned run average and has surrendered 7.5 hits per 9 innings. He has conceded 263 ER's while earning a WHIP of 1.094 and having a FIP of 3.3. He has a K/BB ratio of 3.98 and he has faced 2,923 hitters during his MLB career.
Who will win tonight's MLB game against the spread or moneyline?
Guy Bruhn's Pick: Take St. Louis (-152)
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Additional Resources:
Boston Red Sox - Twitter
St. Louis Cardinals - Twitter