St. Louis Cardinals vs Atlanta Braves Prediction, 4/22/2025 MLB Picks, Best Bets & Odds
Game: St. Louis Cardinals vs Atlanta Braves
Date: Tuesday, April 22, 2025
Location: Truist Park in Cumberland, GA
TV: FanDuel Sports Network South
Odds/Point Spread: St. Louis (-130) Atlanta (+110)
Truist Park is the location where the Atlanta Braves (8-13) will attempt to beat the St. Louis Cardinals (9-13) on Tuesday. The odds on this game have St. Louis at -130 and Atlanta is sitting at +110. The over/under comes in at 9. The pitchers who are expected to start are Andre Pallante and Spencer Strider.


As a team, the St. Louis Cardinals are scoring 4.7 runs per game, which puts them at 8th in baseball. They have tallied 103 runs scored while having a team on-base percentage of .331. The Cardinals have accumulated 42 two-baggers as a squad and have knocked 21 baseballs out of the park. They have accrued 99 runs batted in and 202 hits on the campaign, while their batting average is at .262. St. Louis has a slugging rate of .401 and have been called out on strikes 183 times, while being walked on 75 occasions.
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The Cardinals have compiled a team earned run average of 4.23 on the campaign (20th in the league), and the staff has struck out 158 batters. Cardinals pitchers have conceded 17 long balls and 103 runs (23rd in baseball). Their pitching staff has walked 65 opposing hitters and their FIP sits at 3.61 as a squad on the campaign. St. Louis has surrendered 170 base knocks (7.8 per 9 innings) and also 93 earned runs. Their strikeout to walk ratio is 2.43 and their pitching staff has a collective WHIP of 1.19.
Cardinals pitchers have entered the contest with opponents on base 24 times in addition to having 30 appearances in high leverage situations. The relief pitchers have recorded 12 holds so far this year (20th in baseball). The Cardinals bullpen have compiled a save rate of 55.6% and have entered the game in 21 save situations. They have recorded 5 saves for the season and have blown 4 out of their 9 chances to get a save. The relievers have inherited 24 base runners so far this season and 41.7% of them ended up crossing the plate. The Cardinals have dispatched 73 relief pitchers to the hill so far this season.
The Cardinals have converted 72.4% of baseballs in play into outs out of their 1,779 innings on the diamond, which ranks them 7th in professional baseball. The St. Louis Cardinals have earned a total of 593 putouts at this point in the season, as well as 223 assists and 8 errors. Their fielding percentage is holding steady at .990 which has them sitting 3rd in the majors, and have earned 13 double plays.
Pallante has thrown 319 frames and has earned 225 K's so far in his career. Pallante (20-15 mark in his career) is the owner of a FIP of 3.69 and he has faced 1,357 opposing batters in the major leagues. His ERA is 3.75 (133 ER's allowed) and his WHIP is 1.382. He has surrendered 316 base hits (8.9 hits per nine innings) and has 125 walks.
Atlanta has knocked in 27 home runs for the season to go along with 74 RBIs. They have 26 doubles, while getting a free base 71 times and scoring 77 runs. The Atlanta Braves are sitting with a team on-base percentage of .306 and a team batting average of .230 on the campaign. The Braves hold a slugging percentage of .387 and they are recording 3.67 runs per contest (23rd in the league). They have been called out on strikes on 199 occasions (9th in the league) and have earned a total of 160 base knocks.
The Atlanta pitching staff have relinquished 87 runs for the season while holding a team ERA of 4.25 (85 earned runs yielded). They have given up 28 dingers and they allow 4.35 runs per 9 innings (13th in baseball). The Braves have a team WHIP of 1.305 and have a FIP of 4.42 as a pitching staff over the course of the season. Their K/BB ratio is 8.80 (177 strikeouts against 73 bases on balls). They rank 10th in MLB as a pitching staff in total hits given up with 162.
Atlanta has called on relief pitchers to enter the game in 7 save opportunities and they have come away with 4 saves. They are ranked 22nd in MLB holding a save rate of 57.1%, and they have sent 65 relievers to the hill so far this year. Their relievers have come in 28 times in high leverage situations in addition to 22 occasions with runners on. Atlanta relievers have an inherited score percentage of 40.0% out of their 30 inherited runners. Sitting with 13 save situations, the Braves have compiled 6 holds and also 3 blown saves.
Out of their 1,623 innings on the diamond, the Braves are sitting with a efficiency on defense of 71.3% (12th in pro baseball). The Atlanta Braves have turned 13 double plays and have notched a fielding percentage of .990 (2nd in the majors). The Braves have recorded 177 assists, 7 errors and have accumulated 541 putouts so far this year.
During his MLB career, Strider has surrendered 249 base hits and he has 500 strikeouts in 334 innings. He has surrendered 129 earned runs while earning a WHIP of 1.074 and being the owner of a FIP of 3.4. He has a strikeout to walk ratio of 4.55 and he has gone up against 1,363 opposing batters in his MLB career. Strider (32-11 career mark) has a 3.47 ERA while allowing 6.7 hits per 9 innings.
Who will win tonight's MLB game against the spread or moneyline?
Parlay's Pundit's Pick: Take Atlanta (+110) and under 9 runs
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Additional Resources:
Atlanta Braves - Twitter
St. Louis Cardinals - Twitter