Seattle Mariners vs Boston Red Sox Prediction, 4/23/2025 MLB Picks, Best Bets & Odds
Game: Seattle Mariners vs Boston Red Sox
Date: Wednesday, April 23, 2025
Location: Fenway Park in Boston, MA
TV: NESN
Odds/Point Spread: Seattle (-132) Boston (+110)
The Boston Red Sox (13-11) will try to defeat the Seattle Mariners (12-10) at Fenway Park on Wednesday. The moneyline on this matchup has Seattle at -132 and Boston is priced at +110. The betting total is set at 8. The starting pitchers are Emerson Hancock and Sean Newcomb.


The Mariners have accrued 25 doubles as a unit and have hit 32 balls out of the park. Seattle owns a slugging percentage of .393 and have been called out on strikes 203 times, while drawing a walk on 92 occasions. As a unit, the Seattle Mariners are earning 4.5 runs/g, which is 13th in baseball. They have accrued 91 runs batted in and 163 hits over the course of the season, and their average at the plate is .222. They have tallied 98 runs while holding a team OBP of .319.
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Their strikeout to walk ratio is 2.32 and their pitching staff holds a WHIP of 1.34. Mariners pitchers have surrendered 18 long balls and 93 runs in total (14th in baseball). Seattle has surrendered 194 base hits (8.6 per 9 innings) and also 85 earned runs. The Mariners are sitting with a team ERA of 3.76 for the season (12th in baseball), and they have struck out 183 hitters. They have walked 79 opposing hitters and their FIP is 3.61 as a team over the course of the season.
The Mariners have dispatched 84 relief pitchers to the mound for the season. The relievers have inherited 23 base runners for the year and 30.4% of them crossed the plate. They have compiled 7 saves for the year and have blown 4 out of their 11 chances to save the game. The Mariners relief pitchers have earned a save rate of 63.6% and have entered the game in 25 save situations. The bullpen have racked up 14 holds on the campaign (16th in the league). Mariners relief pitchers have entered the game with runners on 24 times and also have had 34 appearances in high leverage situations.
The Mariners have converted 68.9% of baseballs in play into outs out of their 1,830 innings on the diamond, which ranks them 24th in baseball. The San Francisco Giants have earned 610 putouts so far this season, in addition to 214 assists and 9 errors. Their fielding percentage is holding steady at .989 which has them ranked 5th in pro baseball, and have accumulated 18 double plays.
Hancock has taken the ball for 77 innings and has earned 49 K's so far in his pro baseball career. Hancock (4-5 career win-loss record) has earned a FIP of 5.27 and he has gone up against 342 opposing hitters in the majors. His earned run average is 5.35 (46 earned runs allowed) and his career WHIP is 1.421. He has given up 87 hits (10.1 hits per nine innings) with 23 free passes.
Boston is sitting with 23 long balls on the season as well as 100 RBIs. They have 45 two-baggers, while taking a walk 86 times as well as putting up 104 runs. The Boston Red Sox have accumulated a team on-base percentage of .324 as well as a batting average of .246 this year. The Red Sox hold a team slugging percentage of .394 and they average 4.52 runs per game (11th in the league). They have been called out on strikes on 217 occasions (2nd in the league) and have tallied 195 base knocks.
The Red Sox have a WHIP of 1.292 with a FIP of 3.55 as a squad on the year. Their strikeout to walk ratio sits at 8.40 (192 strikeouts vs 66 walks). They come in at 27th in baseball as a staff in total hits conceded with 199. They have yielded 20 home runs and they allow 4.87 runs per 9 innings (25th in baseball). The Boston pitching staff have surrendered 111 runs over the course of the season while having an ERA of 4.12 (94 earned runs yielded).
Boston relievers have an inherited score rate of 55.6% out of their 27 inherited base runners. Their relief pitchers have stepped onto the hill 25 times in high leverage situations and also on 20 occasions with runners on. Sitting with 18 save situations, the Red Sox have 5 holds and 5 blown saves. They rank 21st in baseball with a save percentage of 58.3%, and they have sent 72 relief pitchers onto the diamond this season. Boston has had relief pitchers enter the contest in 12 save opportunities and they have recorded 7 saves.
The Boston Red Sox have gotten 23 double plays and have a fielding rate of .972 (30th in professional baseball). The Red Sox have 210 assists, 24 errors and have earned 616 putouts over the course of the season. In 1,848 innings on the diamond, the Red Sox have earned a efficiency on defense of 66.7% (28th in baseball).
So far in his MLB career, Newcomb has surrendered 420 hits and he has 457 punch outs in 448 innings. He has allowed 223 ER's while earning a WHIP of 1.484 and being the owner of a FIP of 4.4. His strikeout to walk ratio is 1.87 and he has faced 1,986 opposing batters so far in his career. Newcomb (28-27 win-loss record in his career) has a 4.48 earned run average while giving up 8.4 hits per nine innings.
Who will win tonight's MLB game against the spread or moneyline?
Josh Schonwald's Pick: Take Boston (+110)
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Additional Resources:
Boston Red Sox - Twitter
Seattle Mariners - Twitter