Seattle Mariners vs Boston Red Sox Prediction, 4/22/2025 MLB Picks, Best Bets & Odds

Game: Seattle Mariners vs Boston Red Sox

Date: Tuesday, April 22, 2025

Location: Fenway Park in Boston, MA

TV: NESN

Odds/Point Spread: Seattle (-130) Boston (+110)

The Boston Red Sox (12-11) will try to beat the Seattle Mariners (12-10) at Fenway Park on Tuesday. The moneyline on this contest has Seattle at -130 while Boston opens at +110. The total has been set at 8.5. The expected starting pitchers are Bryce Miller and Brayan Bello.

Seattle has a slugging rate of .393 and have struck out 203 times, while taking a walk on 92 occasions. They have earned 91 RBI's and 163 hits this year, and their average at the plate is .222. The Mariners have accrued 25 doubles as a unit and have smacked 32 balls out of the stadium. They are sitting with 98 runs while having a team on-base percentage of .319. As a team, the Seattle Mariners are knocking in 4.5 runs per outing, which ranks them 13th in MLB.

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They have accrued a K/BB ratio of 2.32 and the pitching staff has earned a collective WHIP of 1.34. Mariners pitchers have surrendered 18 home runs and 93 runs in total (14th in the league). Seattle has allowed 194 base hits (8.6 per 9 innings) in addition to 85 earned runs. The Mariners have an earned run average of 3.76 over the course of the season (12th in baseball), and they have struck out 183 hitters. Their pitching staff has walked 79 opposing players and their FIP comes in at 3.61 as a squad for the season.

The Mariners bullpen have a save percentage of 63.6% and have stepped onto the mound in 25 save situations. The relief pitchers have inherited 23 runners for the season and 30.4% of those runners earned a run for their team. Mariners relief pitchers have stepped onto the hill with runners on 24 times in addition to having 34 appearances in high leverage situations. The Mariners have dispatched 84 relief pitchers to the hill on the year. The relief pitchers have tallied 14 holds this season (16th in MLB). They have accumulated 7 saves for the season and have blown 4 of their 11 chances to save the game.

The Mariners have transformed 68.9% of balls hit into play into outs in their 1,830 innings, ranking them 24th in baseball. The San Francisco Giants are sitting with 610 putouts so far this season, in addition to 214 assists and 9 errors. Their fielding percentage is currently at .989 which has them sitting 5th in professional baseball, and have earned 18 double plays.

Miller has pitched in 332 innings and has earned 311 K's so far in his pro baseball career. Miller (21-17 career mark) sits with a FIP of 3.47 while he has gone up against 1,327 opposing hitters in the majors. His ERA is 3.52 (130 ER's allowed) and his WHIP is 1.066. He has surrendered 273 hits (7.4 hits per 9 innings) and has 81 walks.

The Boston Red Sox have recorded an OBP of .324 in addition to a team batting average of .246 for the season. They have struck out on 217 instances (2nd in the league) and have 195 base hits. Boston has recorded 23 HRs for the year as well as 100 RBIs. The Red Sox have a slugging percentage of .394 and they score 4.52 runs per contest (11th in the league). They have hit 45 doubles, while taking a walk 86 times as well as racking up 104 runs.

The Boston pitching staff have conceded 111 runs on the year while having a team ERA of 4.12 (94 earned runs given up). They have relinquished 20 homers and they concede 4.87 runs per 9 innings (25th in baseball). The Red Sox are sitting with a team WHIP of 1.292 and are the owners of a FIP of 3.55 as a unit on the year. They have earned a strikeout to walk ratio of 8.40 (192 strikeouts vs 66 free passes). They rank 27th in the league as a staff in total hits surrendered with 199.

Sitting with 18 save situations, the Red Sox have earned 5 holds and also 5 blown saves. Boston has had relief pitchers step onto the hill in 12 save opportunities and they have converted 7 saves. Their relief pitchers have stepped onto the mound 25 times in high leverage situations and also on 20 occasions with runners on. Boston relievers hold an inherited score percentage of 55.6% of 27 inherited runners. They are ranked 21st in baseball with a save rate of 58.3%, and they have dispatched 72 relievers onto the field this year.

The Boston Red Sox have turned 23 double plays and have a fielding rate of .972 (30th in professional baseball). The Red Sox have accrued 210 assists, 24 errors and have a total of 616 putouts for the year. In their 1,848 innings on the field, the Red Sox have a defensive efficiency of 66.7% (28th in pro baseball).

So far in his career, Bello has surrendered 397 hits while earning 340 punch outs in 376 innings. Bello (28-27 win-loss mark in his career) holds a 4.43 earned run average while surrendering 9.5 hits per nine innings. He has conceded 185 ER's while holding a WHIP of 1.417 and being the owner of a FIP of 4.4. He has a strikeout to walk ratio of 2.50 and he has faced 1,638 batters so far in his pro baseball career.

Who will win tonight's MLB game against the spread or moneyline?

Josh Schonwald's Pick: Take Boston (+110)

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