San Francisco Giants vs Cincinnati Reds Prediction, 3/27/2025 MLB Picks, Best Bets & Odds

Game: San Francisco Giants vs Cincinnati Reds

Date: Thursday, March 27, 2025

Location: Great American Ball Park in Cincinnati, OH

TV: FanDuel Sports Network Ohio

Odds/Point Spread: San Francisco (-122) Cincinnati (+102)

Great American Ball Park is the site where the Cincinnati Reds (77-85 last season) will try to beat the San Francisco Giants (80-82 last year) on Thursday. The odds on this game have San Francisco at -122 while Cincinnati is sitting at +102. The over/under comes in at 8. The starting pitchers are Logan Webb and Hunter Greene.

As a squad, the San Francisco Giants scored 4.3 runs per game, which had them sitting at 17th in the league. They earned a total of 693 runs while holding a team on-base percentage of .305. The Giants compiled 266 doubles as a team and knocked 177 balls out of the park. They amassed 661 runs batted in and 1,303 hits over the course of the prior season, while their team batting average finished at .239. San Francisco owned a slugging percentage of .396 and were called out on strikes 1,452 times, while being walked on 492 occasions.

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The Giants compiled a team ERA of 4.10 during the previous year (19th in baseball), and their staff struck out 1,436 batters. Giants pitchers yielded 153 home runs and 699 runs (17th in the league). They walked 526 opposing batters and their FIP was 3.80 as a team last season. San Francisco relinquished 1,339 hits (8.4 per 9 innings) in addition to 653 earned runs. They accrued a K/BB ratio of 2.73 and the pitching staff had a collective WHIP of 1.30.

Giants relief pitchers went to the mound with runners on 132 times as well as having 155 contests in high leverage situations. The relief pitchers had 99 holds over the course of last season (7th in baseball). The Giants relievers recorded a save percentage of 65.5% and came into the game in 157 save situations. They compiled 36 saves last season and blew 19 of their 55 save chances. The relievers inherited 194 base runners last year and 35.1% of those players ended up crossing the plate. The Giants dispatched 564 relievers to the hill during the previous year.

The Seattle Mariners accumulated 4,301 putouts for the prior year, in addition to 1,558 assists and 87 errors. Their fielding rate was at .986 which was 10th in the majors, and accumulated 135 double plays. The Giants turned 68.3% of balls in play into outs out of their 12,903 innings on the diamond, which had them ranked 26th in professional baseball.

Webb (55-42 record in his career) holds a FIP of 3.37 and he has gone up against 3,494 hitters during his time in the majors. He has conceded 810 base hits (8.5 hits per 9 innings) and has had 204 free passes. His ERA is 3.42 (325 ER's allowed) and his career WHIP is 1.186. Webb has taken the ball for 855 innings and has 770 K's during his pro baseball career.

Cincinnati knocked in 174 long balls in the prior season to go along with 663 RBIs. They tallied 257 two-baggers, while taking a walk 496 times and scoring 699 runs. The Cincinnati Reds accumulated an on-base percentage of .305 and a team batting average of .231 over the course of last season. The Reds held a slugging % of .388 and they scored 4.31 runs per contest (16th in the league). They were rung up on 1,459 occasions (9th in the league) and recorded 1,230 base hits.

The Reds held a team WHIP of 1.253 with a FIP of 4.25 as a squad over the course of the prior season. They earned a K/BB ratio of 8.60 (1,370 strikeouts vs 487 bases on balls). They were sitting at 13th in MLB as a pitching staff in total hits allowed with 1,302. They surrendered 196 HR's and they surrendered 4.37 runs per 9 innings (16th in MLB). The Cincinnati pitching staff conceded 694 runs over the course of the prior season while having an ERA of 4.09 (649 earned runs surrendered).

Cincinnati relievers had an inherited score rate of 31.1% out of 225 inherited base runners. Their relievers took the field 155 times in high leverage situations in addition to 145 occasions with base runners. With 132 save situations, the Reds earned 78 holds in addition to 15 blown saves. They were sitting at 3rd in the league with a save rate of 70.6%, and they sent 534 relief pitchers to the mound last year. Cincinnati had relief pitchers enter the contest in 51 save chances and they walked away with 36 saves.

Out of their 12,852 innings played, the Reds had a defensive efficiency of 70.2% (15th in baseball). The Cincinnati Reds had 100 double plays and owned a fielding percentage of .983 (27th in MLB). The Reds had 1,213 assists, 96 errors and a tally of 4,284 putouts for the prior year.

So far in his career, Greene has given up 311 base hits while earning 485 strikeouts in 388 frames. Greene (18-25 mark in his career) has earned a 3.90 ERA while allowing 7.2 hits per nine innings. He has given up a total of 168 ER's while earning a WHIP of 1.196 and having a FIP of 3.8. His strikeout to walk ratio is 3.17 and he has faced 1,640 opposing hitters in his MLB career.

Who will win tonight's MLB game against the spread or moneyline?

Guy Bruhn's Pick: Take San Francisco (-122)

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