San Diego Padres vs Houston Astros Prediction, 4/18/2025 MLB Picks, Best Bets & Odds

Game: San Diego Padres vs Houston Astros

Date: Friday, April 18, 2025

Location: Daikin Park in Houston, TX

TV: Space City Home Network

Odds/Point Spread: San Diego (-150) Houston (+125)

The San Diego Padres (15-4) are en route to Daikin Park on Friday where they will take on the Houston Astros (8-10). The line on this contest has San Diego at -150 and Houston is priced at +125. The total is 8.5. The pitchers who are expected to start will be Kyle Hart and Ryan Gusto.

As a team, the San Diego Padres are earning 4.6 runs per outing, which puts them at 8th in baseball. They have racked up 88 runs and have an OBP of .348. The Padres have accumulated 32 two-baggers as a unit and have smacked 19 baseballs out of the park. They have 80 runs batted in as well as 171 hits this season, while their team batting average comes in at .274. San Diego is slugging .417 and have struck out 124 times, while drawing a walk on 70 occasions.

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The Padres are sitting with a team earned run average of 2.56 so far this season (2nd in baseball), and their staff has rung up 165 batters. Padres pitchers have conceded 13 home runs and 51 runs in total (1st in the league). They have walked 64 batters and their FIP sits at 3.26 as a unit so far this year. San Diego has allowed 117 base knocks (6.2 per 9 innings) and 48 earned runs. They have accumulated a K/BB ratio of 2.58 and their pitching staff holds a collective WHIP of 1.07.

Padres pitchers have stepped onto the hill with runners on base 15 times and also have had 29 appearances in high leverage situations. The relievers have recorded 17 holds for the year (4th in baseball). The Padres relief pitchers have accumulated a save percentage of 90.0% and has come into the game in 27 save situations. They have compiled 9 saves on the year and have blown 1 of their 10 chances to save the game. The relievers have inherited 22 runners on the year and 27.3% of those runners crossed the plate. The Padres have sent 65 relief pitchers to the mound on the year.

The San Diego Padres have amassed 507 putouts so far this season, as well as 140 assists and 9 errors. Their fielding percentage is holding at .986 which ranks 13th in pro baseball, and they have turned 14 double plays. The Padres have transformed 74.7% of balls hit into play into outs in their 1,521 innings, ranking them 2nd in professional baseball.

Hart has taken the hill for 22 innings and is sitting with 21 strikeouts so far in his pro baseball career. His ERA is 10.54 (26 earned runs allowed) and he has a career WHIP of 2.117. He has given up 32 base hits (13.0 hits per nine innings) with 15 free passes. Hart (2-1 career record) is the owner of a FIP of 10.38 while going up against 113 hitters during his time in the majors.

The Astros hold a team slugging percentage of .317 and they are scoring 3.67 runs per game (23rd in baseball). They have recorded 16 doubles, while walking 66 times and earning 66 runs. Houston is sitting with 14 home runs so far this season and 59 RBIs. They have been called out on strikes on 152 occasions (16th in baseball) and have totaled 127 hits. The Houston Astros have recorded an on-base percentage of .300 as well as a team batting average of .216 so far this season.

The Astros are sitting with a team WHIP of 1.129 in addition to having a FIP of 3.38 as a team this season. They have earned a strikeout to walk ratio of 10.10 (181 strikeouts against 59 walks). They have a ranking of 5th in the league as a pitching staff in total hits conceded with 123. They have allowed 17 homers and they concede 3.91 runs per 9 innings (9th in MLB). The Houston pitching staff have given up 70 runs for the season while holding a team ERA of 3.74 (67 earned runs surrendered).

Houston has called on relievers to enter the game in 8 save opportunities and they have earned 5 saves. They sit at 15th in the league holding a save percentage of 62.5%, and they have dispatched 59 relief pitchers onto the field so far this season. Their bullpen pitchers have stepped onto the hill 18 times in high leverage situations in addition to 16 occasions with base runners. Houston bullpen pitchers hold an inherited score percentage of 34.8% out of their 23 inherited runners. Sitting with 20 save situations, the Astros have earned 12 holds in addition to 3 blown saves.

The Houston Astros have turned 9 double plays and have notched a fielding percentage of .986 (17th in professional baseball). The Astros have accrued 130 assists, 9 errors and have a total of 485 putouts so far this year. In their 1,455 innings played, the Astros have earned a defensive efficiency of 72.2% (9th in the majors).

Gusto (1-1 record in his career) has a 3.00 earned run average while giving up 6.8 hits per nine innings. He has a K/BB ratio of 5.00 and he has faced 47 hitters during his pro baseball career. He has conceded a total of 4 ER's while earning a WHIP of 1.000 and being the owner of a FIP of 3.0. During his pro baseball career, Gusto has conceded 9 base hits while he has accumulated 15 strikeouts in 12 innings.

Who will win tonight's MLB game against the spread or moneyline?

Guy Bruhn's Pick: Take Houston (+125)

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