Philadelphia Phillies vs Chicago Cubs Prediction, 4/25/2025 MLB Picks, Best Bets & Odds
Game: Philadelphia Phillies vs Chicago Cubs
Date: Friday, April 25, 2025
Location: Wrigley Field in Chicago, IL
TV: Marquee
Odds/Point Spread: Philadelphia (+120) Chicago (-144)
The Philadelphia Phillies (13-12) are headed to Wrigley Field on Friday where they will take on the Chicago Cubs (16-10). The odds on this game have the Phillies at +120 and the Cubs are coming in at -144. The over/under has been set at 8.5. The pitchers who are expected to start will be Taijuan Walker and Colin Rea.


As a unit, the Philadelphia Phillies are compiling 4.4 runs per contest, which is 12th in baseball. They have notched a total of 111 runs scored and have an on-base percentage of .340. The Phillies have tallied 38 two-baggers as a squad and have knocked 21 baseballs out of the park. They have compiled 104 runs batted in as well as 212 hits so far this season, and their team batting average comes in at .251. Philadelphia has a slugging percentage of .381 and have struck out 206 times, while being walked on 108 occasions.
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Their strikeout to walk ratio sits at 3.28 and the pitching staff holds a collective WHIP of 1.34. Phillies pitchers have given up 31 home runs and also 115 total runs (22nd in MLB). Philadelphia has surrendered 222 hits (9.0 per 9 innings) and also 107 earned runs. The Phillies have compiled a team ERA of 4.32 on the season (21st in the league), and they have rung up 246 batters. They have walked 75 batters and their FIP comes in at 3.76 as a unit for the year.
Phillies relief pitchers have entered the contest with opponents on base 15 times in addition to having 28 appearances in high leverage situations. The relievers have racked up 14 holds for the season (18th in baseball). The Phillies relief pitchers have earned a save rate of 50.0% and have entered the game in 29 save situations. They have recorded 7 saves so far this season and have not converted 7 out of their 14 save opportunities. The relief pitchers have inherited 21 runners on the season with 42.9% of those players crossed the plate. The Phillies have dispatched 81 relievers to the hill so far this year.
The Philadelphia Phillies have earned a total of 668 putouts on the year, as well as 212 assists and 10 errors. Their fielding percentage is holding steady at .989 which is 5th in MLB, and have a total of 19 double plays. The Phillies have transformed 66.8% of balls in play into outs in their 2,004 innings on the field, which has them ranked 27th in baseball.
Walker (73-64 career win-loss mark) has earned a FIP of 4.10 while he has faced 4,968 hitters in the majors. He has given up 1,094 base hits (8.4 hits per 9 innings) with 400 walks. His earned run average is 4.17 (543 earned runs allowed) and his career WHIP is 1.273. Walker has thrown 1,173 frames and has totaled 1,018 K's in his career.
The Chicago Cubs hold a team on-base percentage of .346 and a team batting average of .265 on the season. They have struck out on 217 instances (11th in the league) and have totaled 243 hits. Chicago has knocked in 38 long balls over the course of the season as well as 160 RBIs. The Cubs hold a slugging % of .460 and they are earning 6.27 runs per contest (1st in baseball). They have put up 49 two-baggers, while getting a free base 108 times as well as earning 163 runs.
The Chicago pitching staff have conceded 120 runs for the year while having an ERA of 4.17 (108 earned runs conceded). They have yielded 32 dingers and they allow 4.64 runs per 9 innings (18th in baseball). The Cubs have a WHIP of 1.365 in addition to having a FIP of 4.32 as a pitching staff on the campaign. Their strikeout to walk ratio sits at 8.00 (206 strikeouts against 92 free passes). They are sitting at 29th in the league as a staff in total hits given up with 226.
Chicago has called on bullpen pitchers to enter the game in 13 save opportunities and they have recorded 7 saves. They are ranked 24th in the league with a save percentage of 53.8%, and they have sent 90 relief pitchers to the mound this year. Their relievers have stepped onto the hill 30 times in high leverage situations in addition to 21 occasions with runners on base. Chicago bullpen pitchers have an inherited score rate of 43.3% out of 30 inherited runners. With 31 save situations, the Cubs have accumulated 17 holds in addition to 6 blown saves.
Out of their 2,097 innings played, the Cubs have accumulated a defensive efficiency of 69.5% (21st in professional baseball). The Chicago Cubs have gotten 16 double plays and have a fielding percentage of .982 (24th in pro baseball). The Cubs have accrued 204 assists, 17 errors and have accounted for 699 putouts so far this year.
So far in his career, Rea has given up 446 hits while he has earned 378 punch outs in 459 frames. He has surrendered 229 ER's while holding a WHIP of 1.273 and a FIP of 4.4. His K/BB ratio is 2.72 and he has gone up against 1,960 opposing hitters in his MLB career. Rea (26-20 win-loss record in his career) is the owner of a 4.49 ERA while giving up 8.7 hits per nine innings.
Who will win tonight's MLB game against the spread or moneyline?
Josh Schonwald's Pick: Take Philadelphia (+120)
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Additional Resources:
Chicago Cubs - Twitter
Philadelphia Phillies - Twitter