New York Yankees vs Cleveland Guardians Prediction, 4/22/2025 MLB Picks, Best Bets & Odds

Game: New York Yankees vs Cleveland Guardians

Date: Tuesday, April 22, 2025

Location: Progressive Field in Cleveland, OH

TV: CLEGuardians.TV

Odds/Point Spread: New York (-144) Cleveland (+120)

Progressive Field is the site where the Cleveland Guardians (12-9) will take on the New York Yankees (14-8) on Tuesday. The odds on this game have the Yankees at -144 and the Guardians are sitting at +120. The total is 8.5. The expected starting pitchers are Will Warren and Tanner Bibee.

New York has a slugging % of .467 and have struck out 206 times, while taking a walk on 85 occasions. They have tallied 121 RBI's as well as 189 hits for the year, and their average at the plate sits at .257. The Yankees have compiled 34 two-baggers as a team and have hit 38 baseballs out of the stadium. They have earned 126 runs scored and hold an on-base percentage of .342. As a unit, the New York Yankees are notching 5.7 runs per game, which has them at 2nd in MLB.

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They have a K/BB ratio of 2.20 and their pitching staff sits with a WHIP of 1.21. Yankees pitchers have allowed 22 long balls in addition to 96 runs in total (17th in the league). New York has given up 140 base hits (6.5 per 9 innings) and 86 earned runs. The Yankees hold a team earned run average of 3.99 on the campaign (14th in MLB), and they have struck out 209 batters. They have walked 95 batters and their FIP sits at 3.88 as a team this year.

Yankees bullpen pitchers have stepped onto the hill with opponents on base 27 times as well as having 19 appearances in high leverage situations. The relief pitchers have tallied 17 holds on the year (8th in the league). The Yankees bullpen have recorded a save percentage of 90.0% and stepped onto the hill in 27 save situations. They have 9 saves this season and have missed out on 1 out of their 10 save opportunities. The relief pitchers have inherited 36 runners for the year and 11.1% of those players earned a run for their team. The Yankees have dispatched 72 relief pitchers to the hill this year.

The Yankees have transformed 73.8% of balls hit into play into outs in their 1,746 innings, which ranks them 3rd in professional baseball. The New York Mets are sitting with 582 putouts thus far, as well as 182 assists and 11 errors. Their fielding percentage is holding at .986 which is 16th in baseball, and they have turned 14 double plays.

Warren has thrown 37 frames and has tallied 45 K's during his pro baseball career. His ERA is 8.42 (35 ER's allowed) and he has a career WHIP of 1.738. He has given up 46 base knocks (11.1 hits per nine innings) and has had 19 free passes. Warren (1-3 mark in his career) has earned a FIP of 8.30 and he has faced 177 opposing batters in the majors.

Cleveland is sitting with 26 home runs so far this season to go along with 82 RBIs. They have tallied 26 two-baggers, while walking 70 times and scoring 86 runs. The Cleveland Guardians have compiled a team OBP of .310 as well as a batting average of .238 for the season. The Guardians hold a team SLG% of .396 and they are earning 4.10 runs per contest (21st in MLB). They have been called out on strikes on 165 occasions (26th in the league) and have totaled 162 base knocks.

The Guardians are sitting with a team WHIP of 1.350 in addition to having a FIP of 4.26 as a squad on the season. They currently have a strikeout to walk ratio of 8.70 (177 strikeouts vs 75 free passes). They are sitting at 16th in the league as a staff in total hits surrendered with 172. They have surrendered 26 HR's and they surrender 4.43 runs per 9 innings (15th in MLB). The Cleveland pitching staff have relinquished 90 runs so far this year while having an ERA of 3.98 (81 earned runs relinquished).

With 32 save situations, the Guardians have accrued 23 holds and 3 blown saves. Cleveland has had relief pitchers enter the game in 9 save chances and they have converted 6 saves. Their relief pitchers have stepped onto the mound 18 times in high leverage situations and on 22 occasions with base runners. Cleveland relief pitchers hold an inherited score percentage of 13.3% out of 30 inherited runners. They rank 13th in the league holding a save percentage of 66.7%, and they have sent 76 bullpen pitchers onto the diamond over the course of the season.

The Cleveland Guardians have turned 18 double plays and have accounted for a fielding rate of .983 (23rd in pro baseball). The Guardians have racked up 156 assists, 12 errors and have earned 549 putouts on the season. Out of their 1,647 innings on the diamond, the Guardians are sitting with a defensive efficiency of 69.0% (23rd in the majors).

In his pro baseball career, Bibee has surrendered 291 base hits while totaling 343 strikeouts in 335 innings pitched. He has surrendered a total of 127 ER's while earning a WHIP of 1.166 and having a FIP of 3.4. He has a strikeout to walk ratio of 3.43 and he has faced 1,382 hitters so far in his MLB career. Bibee (23-14 career mark) has earned a 3.41 ERA and has conceded 7.8 hits per 9 innings.

Who will win tonight's MLB game against the spread or moneyline?

Guy Bruhn's Pick: Take Cleveland (+120)

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