New York Yankees vs Cleveland Guardians Prediction, 4/21/2025 MLB Picks, Best Bets & Odds

Game: New York Yankees vs Cleveland Guardians

Date: Monday, April 21, 2025

Location: Progressive Field in Cleveland, OH

TV: CLEGuardians.TV

Odds/Point Spread: New York (-150) Cleveland (+125)

Progressive Field is the site where the Cleveland Guardians (9-9) will try to beat the New York Yankees (12-7) on Monday. The odds on this game have the Yankees at -150 and the Guardians are coming in at +125. The betting total is set at 9. The starting pitchers are Clarke Schmidt and Gavin Williams.

The Yankees have accumulated 32 two-baggers as a team and have smacked 34 balls out of the park. New York has a slugging % of .481 and have been called out on strikes 174 times, while being walked on 73 occasions. As a team, the New York Yankees are notching 6.0 runs per outing, which has them at 1st in baseball. They have earned 109 runs batted in and 165 base knocks this year, and their batting average comes in at .260. They have tallied 113 runs scored and hold an OBP of .345.

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They have a strikeout to walk ratio of 2.28 and the pitching staff holds a WHIP of 1.23. Yankees pitchers have conceded 21 long balls and also 86 total runs (21st in the league). New York has yielded 124 hits (6.7 per 9 innings) and 77 earned runs. The Yankees have a team ERA of 4.15 for the season (20th in baseball), and their staff has rung up 187 batters. They have walked 82 opposing players and their FIP comes in at 3.92 as a unit so far this year.

Yankees pitchers have come into the game with runners on 24 times and also have had 12 appearances in high leverage situations. The bullpen have tallied 13 holds on the campaign (14th in baseball). The Yankees relief pitchers have a save percentage of 87.5% and have stepped onto the mound in 21 save situations. They have compiled 7 saves on the year and have not converted 1 out of their 8 save chances. The bullpen pitchers have inherited 34 base runners so far this year with 11.8% of them earned a run for their team. The Yankees have sent 63 relievers to the mound on the season.

The New York Mets are sitting with 501 putouts this season, in addition to 146 assists and 8 errors. Their fielding percentage sits at .988 which puts them in 8th in MLB, and have earned 9 double plays. The Yankees have converted 73.6% of balls hit into play into outs out of their 1,503 innings on the diamond, which has them ranked 5th in pro baseball.

Schmidt has pitched in 319 innings and has totaled 313 strikeouts so far in his career. Schmidt (19-20 record in his career) is the owner of a FIP of 3.91 and he has gone up against 1,377 opposing batters in the major leagues. His earned run average is 3.97 (141 ER's allowed) and he has a WHIP of 1.312. He has allowed 308 hits (8.7 hits per nine innings) with 111 free passes.

Cleveland is sitting with 22 home runs over the course of the season as well as 64 RBIs. They have hit 17 two-baggers, while getting a free base 61 times as well as scoring 68 runs. The Cleveland Guardians are sitting with an on-base percentage of .304 as well as a batting average of .228 this season. The Guardians have a SLG% of .380 and they average 3.78 runs per game (22nd in the league). They have been rung up on 145 occasions (24th in baseball) and have recorded 131 hits.

The Cleveland pitching staff have conceded 79 runs on the campaign and come in with a team ERA of 4.06 (70 earned runs conceded). They have yielded 23 homers and they relinquish 4.59 runs per 9 innings (21st in the league). The Guardians hold a team WHIP of 1.348 and are the owners of a FIP of 4.37 as a team so far this season. Their K/BB ratio sits at 8.60 (148 strikeouts against 65 free passes). They sit at 14th in MLB as a staff in total hits relinquished with 144.

Cleveland has had bullpen pitchers enter the contest in 5 save opportunities and they have come away with 3 saves. They are ranked 17th in the league with a save percentage of 60.0%, and they have dispatched 62 relievers onto the diamond so far this year. Their bullpen pitchers have taken the field 14 times in high leverage situations and also on 17 occasions with base runners. Cleveland relievers have an inherited score rate of 16.7% out of their 24 inherited base runners. Sitting with 21 save situations, the Guardians have tallied 16 holds and also 2 blown saves.

Out of their 1,395 innings played, the Guardians have earned a efficiency on defense of 69.5% (23rd in the majors). The Cleveland Guardians have turned 15 double plays and have a fielding percentage of .982 (23rd in pro baseball). The Guardians have recorded 131 assists, 11 errors and have amassed 465 putouts this year.

Williams (7-16 career record) has a 4.11 earned run average while allowing 7.8 hits per nine innings. His strikeout to walk ratio is 2.25 and he has faced 760 opposing batters in his career. He has allowed 81 ER's while earning a WHIP of 1.315 and having a FIP of 4.1. Thus far in his career, Williams has surrendered 154 hits while accumulating 178 K's in 177 innings pitched.

Who will win tonight's MLB game against the spread or moneyline?

Parlay's Pundit's Pick: Take Cleveland (+125) and under 9 runs

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