Milwaukee Brewers vs St. Louis Cardinals Prediction, 4/26/2025 MLB Picks, Best Bets & Odds
Game: Milwaukee Brewers vs St. Louis Cardinals
Date: Saturday, April 26, 2025
Location: Busch Stadium in St. Louis, MO
TV: FanDuel Sports Network Midwest
Odds/Point Spread: Milwaukee (-196) St. Louis (+162)
The St. Louis Cardinals (10-15) welcome the Milwaukee Brewers (13-12) at Busch Stadium on Saturday. The odds on this game have the Brewers at -196 while the Cardinals are sitting at +162. The over/under has been set at 8.5. The pitchers taking the mound are Quinn Priester and Sonny Gray.


As a team, the Milwaukee Brewers are knocking in 5.1 runs per game, which has them at 5th in MLB. They have earned 127 runs scored while holding a team OBP of .318. The Brewers have accrued 31 doubles as a team and have hit 25 baseballs out of the park. They have 112 RBI's and 205 base knocks this year, while their average at the plate comes in at .244. Milwaukee has a slugging percentage of .380 and have been called out on strikes 202 times, while being walked on 83 occasions.
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They have a strikeout to walk ratio of 2.18 and the pitching staff has a collective WHIP of 1.32. Brewers pitchers have relinquished 31 home runs and 113 total runs (21st in the league). Milwaukee has given up 194 base knocks (8.0 per 9 innings) in addition to 101 earned runs. The Brewers have a team earned run average of 4.14 on the year (18th in MLB), and their staff has struck out 207 batters. Their pitching staff has walked 95 opposing players and their FIP sits at 4.41 as a squad on the campaign.
Brewers pitchers have stepped onto the hill with runners on base 21 times in addition to having 18 appearances in high leverage situations. The bullpen have recorded 15 holds on the year (16th in the league). The Brewers relievers have recorded a save rate of 66.7% and have entered the game in 22 save situations. They have compiled 4 saves for the season and have blown 2 out of their 6 save opportunities. The relievers have inherited 32 runners so far this year with 50.0% of them ended up crossing the plate. The Brewers have sent 87 relievers to the hill for the year.
The Brewers have turned 71.1% of balls in play into outs in their 1,977 innings on the diamond, which has them sitting 10th in professional baseball. The Miami Marlins are sitting with 659 putouts this season, in addition to 182 assists and 15 errors. Their fielding percentage is holding steady at .982 which is 22nd in professional baseball, and have accumulated 20 double plays.
Priester (7-9 career record) holds a FIP of 5.64 while going up against 514 opposing batters in the major leagues. He has surrendered 125 base hits (9.9 hits per 9 innings) and has 50 free passes. His ERA is 5.72 (72 earned runs allowed) and his career WHIP is 1.546. Priester has taken the mound for 113 frames and has earned 80 K's during his MLB career.
The St. Louis Cardinals have compiled an on-base percentage of .335 and a batting average of .264 on the year. They have struck out on 202 occasions (17th in MLB) and have 232 hits. St. Louis has knocked in 23 home runs on the year to go along with 114 runs batted in. The Cardinals have a team SLG% of .403 and they score 4.80 runs per game (7th in baseball). They have recorded 51 doubles, while walking 88 times and notching 120 runs.
The Cardinals are sitting with a team WHIP of 1.238 with a FIP of 3.86 as a unit this year. They have earned a K/BB ratio of 7.10 (175 strikeouts vs 78 walks). They are currently ranked 20th in the league as a pitching staff in total hits conceded with 197. They have conceded 22 HR's and they concede 4.78 runs per 9 innings (23rd in baseball). The St. Louis pitching staff have allowed 118 runs over the course of the season and come in with a team ERA of 4.37 (108 earned runs yielded).
St. Louis relievers have an inherited score rate of 50.0% out of 30 inherited runners. Their relievers have stepped onto the mound 37 times in high leverage situations in addition to 27 occasions with runners on. With 25 save situations, the Cardinals have 14 holds and 6 blown saves. They rank 27th in baseball with a save percentage of 45.5%, and they have sent 83 relievers to the hill on the season. St. Louis has called on relief pitchers to step onto the mound in 11 save opportunities and they have tallied 5 saves.
The St. Louis Cardinals have turned 15 double plays and have a fielding rate of .989 (3rd in pro baseball). The Cardinals have racked up 247 assists, 10 errors and have a tally of 668 putouts for the season. In their 2,004 innings played, the Cardinals have accumulated a defensive efficiency of 72.1% (7th in baseball).
Gray (114-94 mark in his career) is the owner of a 3.51 ERA and has conceded 7.7 hits per nine innings. His K/BB ratio is 2.99 and he has faced 7,310 batters in his pro baseball career. He has given up 688 ER's while holding a WHIP of 1.188 and a FIP of 3.5. So far in his pro baseball career, Gray has surrendered 1,511 base hits while totaling 1,753 punch outs in 1,766 frames.
Who will win tonight's MLB game against the spread or moneyline?
Guy Bruhn's Pick: Take St. Louis (+162)
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Additional Resources:
St. Louis Cardinals - Twitter
Milwaukee Brewers - Twitter