Los Angeles Dodgers vs Chicago Cubs Prediction, 4/23/2025 MLB Picks, Best Bets & Odds
Game: Los Angeles Dodgers vs Chicago Cubs
Date: Wednesday, April 23, 2025
Location: Wrigley Field in Chicago, IL
TV: Marquee
Odds/Point Spread: Los Angeles (-152) Chicago (+126)
The Los Angeles Dodgers (16-7) are traveling to Wrigley Field on Wednesday where they will take on the Chicago Cubs (14-10). The moneyline on this contest has the Dodgers at -152 while the Cubs are priced at +126. The total has been set at 8.5. The expected starting pitchers will be Yoshinobu Yamamoto and Matthew Boyd.


As a team, the Los Angeles Dodgers are earning 4.4 runs per contest, which ranks them 15th in MLB. They have tallied 100 runs while having a team on-base percentage of .311. The Dodgers have accumulated 27 two-baggers as a team and have smacked 36 baseballs out of the park. They have recorded 97 RBI's as well as 168 base knocks for the year, while their team batting average is at .227. Los Angeles is slugging .415 and have been called out on strikes 192 times, while taking a walk on 82 occasions.
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The Dodgers hold a team ERA of 3.55 this year (7th in baseball), and their staff has struck out 222 batters. Dodgers pitchers have allowed 21 long balls and 90 total runs (12th in MLB). Their pitching staff has walked 88 opposing hitters and their FIP is 3.57 as a team for the year. Los Angeles has given up 163 hits (7.2 per 9 innings) as well as 80 earned runs. They have earned a strikeout to walk ratio of 2.52 and their pitching staff has a collective WHIP of 1.24.
Dodgers relief pitchers have entered the contest with runners on base 13 times in addition to having 29 appearances in high leverage situations. The bullpen have tallied 26 holds on the season (1st in baseball). The Dodgers relief pitchers have earned a save rate of 78.6% and have stepped onto the mound in 42 save situations. They have accumulated 11 saves on the year and have blown 3 of their 14 chances to get a save. The relief pitchers have inherited 18 base runners over the course of the season with 22.2% of those players ended up scoring. The Dodgers have dispatched 88 relief pitchers to the mound for the season.
The Los Angeles Angels have notched a total of 609 putouts this year, as well as 186 assists and 9 errors. Their fielding percentage is holding at .989 which has them ranked 6th in professional baseball, and have accumulated 14 double plays. The Dodgers have converted 71.1% of balls hit into play into outs out of 1,827 innings, which has them ranked 15th in pro baseball.
Yamamoto has taken the mound for 119 innings and has 143 strikeouts so far in his MLB career. Yamamoto (10-3 win-loss record in his career) has a FIP of 2.46 while going up against 476 opposing hitters in the major leagues. His earned run average is 2.50 (33 ER's allowed) and his career WHIP is 1.050. He has surrendered 96 hits (7.3 hits per 9 innings) and has 29 walks.
Chicago has tallied 34 home runs so far this season to go along with 142 runs batted in. They have put up 44 doubles, while taking a walk 97 times and earning 145 runs. The Chicago Cubs have an on-base percentage of .338 and a batting average of .258 for the season. The Cubs hold a slugging percentage of .447 and they average 6.04 runs per game (1st in baseball). They have struck out on 197 occasions (10th in the league) and are sitting with 218 hits.
The Cubs are sitting with a team WHIP of 1.369 with a FIP of 4.23 as a unit on the year. They currently have a strikeout to walk ratio of 7.90 (188 strikeouts vs 87 walks). They are sitting at 29th in baseball as a pitching staff in total hits surrendered with 206. They have yielded 27 homers and they allow 4.37 runs per 9 innings (14th in baseball). The Chicago pitching staff have relinquished 104 runs on the year while having an ERA of 4.16 (99 earned runs yielded).
Chicago has had relief pitchers step onto the hill in 11 save chances and they have walked away with 6 saves. They are ranked 24th in MLB holding a save percentage of 54.5%, and they have dispatched 83 relievers onto the field so far this season. Their relievers have taken the field 26 times in high leverage situations and on 19 occasions with runners on. Chicago relief pitchers hold an inherited score rate of 39.3% out of 28 inherited runners. With 27 save situations, the Cubs have earned 15 holds and also 5 blown saves.
The Chicago Cubs have gotten 14 double plays and have a fielding rate of .984 (21st in pro baseball). The Cubs have racked up 193 assists, 14 errors and have a total of 642 putouts over the course of the season. Out of their 1,926 innings on the diamond, the Cubs hold a efficiency on defense of 69.6% (20th in MLB).
Boyd (47-71 career mark) is the owner of a 4.78 ERA while allowing 8.9 hits per 9 innings. He has a strikeout to walk ratio of 3.01 and he has faced 3,991 batters thus far in his career. He has allowed 494 ER's while earning a WHIP of 1.313 and a FIP of 4.7. In his pro baseball career, Boyd has allowed 918 base hits while earning 911 strikeouts in 930 innings.
Who will win tonight's MLB game against the spread or moneyline?
Guy Bruhn's Pick: Take Los Angeles (-152)
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Additional Resources:
Chicago Cubs - Twitter
Los Angeles Dodgers - Twitter