Houston Astros vs Minnesota Twins Prediction, 4/6/2025 MLB Picks, Best Bets & Odds
Game: Houston Astros vs Minnesota Twins
Date: Sunday, April 6, 2025
Location: Target Field in Minneapolis, MN
TV: Twins.TV
Odds/Point Spread: Houston (-144) Minnesota (+120)
The Houston Astros (3-4) are traveling to Target Field on Sunday where they will compete against the Minnesota Twins (2-5). The line on this contest has the Astros at -144 while the Twins are sitting at +120. The total is set at 9. The starting pitchers will be Ronel Blanco and Chris Paddack.


The Astros have hit 5 two-baggers as a unit and have knocked 4 baseballs out of the park. Houston is slugging .270 and have struck out 66 times, while being walked on 21 occasions. As a unit, the Houston Astros are earning 2.4 runs per contest, which puts them at 28th in baseball. They have 16 runs batted in and 41 base knocks for the year, and their team batting average is .191. They are sitting with 17 runs while holding a team OBP of .274.
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They have a strikeout to walk ratio of 2.85 and their pitching staff has earned a collective WHIP of 1.00. Astros pitchers have yielded 6 home runs in addition to 23 total runs (8th in MLB). Houston has surrendered 36 base hits (5.1 per 9 innings) and 22 earned runs. The Astros hold a team earned run average of 3.14 for the year (10th in the league), and they have rung up 77 batters. They have walked 27 hitters and their FIP comes in at 3.07 as a unit on the campaign.
The Astros relief pitchers have earned a save rate of 100.0% and stepped onto the hill in 8 save situations. The relief pitchers have inherited 4 runners so far this year and 25.0% of them crossed the plate. Astros pitchers have entered the contest with players on base 3 times as well as having 3 appearances in high leverage situations. The Astros have dispatched 21 relievers to the mound on the year. The relievers have accumulated 5 holds so far this season (12th in baseball). They have accumulated 3 saves over the course of the season and have not converted 0 of their 3 save opportunities.
The Astros have turned 76.5% of balls in play into outs out of their 567 innings on the diamond, which has them sitting 5th in the majors. The Detroit Tigers have earned a total of 189 putouts on the year, as well as 54 assists and 4 errors. Their fielding rate is at .984 which has them sitting 19th in baseball, and have accumulated 4 double plays.
Blanco (15-8 win-loss record in his career) holds a FIP of 3.31 and he has faced 955 opposing hitters during his time in the majors. He has given up 174 base knocks (6.8 hits per 9 innings) with 103 free passes. His earned run average is 3.36 (86 earned runs allowed) and his career WHIP is 1.203. Blanco has taken the mound for 230 frames and is sitting with 231 K's so far in his pro baseball career.
The Minnesota Twins have accounted for an on-base percentage of .240 in addition to a team batting average of .180 for the season. They have been rung up on 54 occasions (17th in baseball) and have tallied 41 base hits. Minnesota has hit 5 home runs so far this season to go along with 22 runs batted in. The Twins have a team slugging % of .294 and they earn 3.14 runs per contest (24th in MLB). They have put up 9 two-baggers, while walking 15 times and putting up 22 runs.
The Twins have a team WHIP of 1.373 with a FIP of 4.77 as a pitching staff on the season. They are sitting at 28th in MLB as a pitching staff in total hits conceded with 62. The Minnesota pitching staff have surrendered 37 runs on the year while holding a team ERA of 5.34 (35 earned runs yielded). Their K/BB ratio sits at 8.50 (56 strikeouts against 19 walks). They have yielded 12 long balls and they allow 5.64 runs per 9 innings (27th in baseball).
Minnesota relievers have an inherited score percentage of 37.5% out of 8 inherited runners. Their relief pitchers have come in 3 times in high leverage situations and on 5 occasions with runners on. Sitting with 3 save situations, the Twins have compiled 3 holds and also 0 blown saves. They are currently ranked 30th in baseball holding a save rate of 0.0%, and they have sent 23 bullpen pitchers to the mound for the season. Minnesota has had relief pitchers take the mound in 0 save chances.
The Minnesota Twins have turned 4 double plays and have notched a fielding percentage of .986 (16th in professional baseball). The Twins have accrued 37 assists, 3 errors and have a total of 177 putouts on the campaign. In their 531 innings played, the Twins are sitting with a efficiency on defense of 69.0% (21st in the majors).
Paddack (27-25 win-loss record in his career) has a 4.54 ERA while conceding 8.9 hits per nine innings. He has a strikeout to walk ratio of 4.51 and he has faced 1,791 hitters during his career. He has given up a total of 215 ER's while earning a WHIP of 1.206 and a FIP of 4.5. Thus far in his career, Paddack has conceded 421 hits while earning 419 strikeouts in 426 innings.
Who will win tonight's MLB game against the spread or moneyline?
Josh Schonwald's Pick: Take Houston (-144)
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Additional Resources:
Minnesota Twins - Twitter
Houston Astros - Twitter