Cleveland Guardians vs San Diego Padres Prediction, 4/2/2025 MLB Picks, Best Bets & Odds

Game: Cleveland Guardians vs San Diego Padres

Date: Wednesday, April 2, 2025

Location: Petco Park in San Diego, CA

TV: Padres.TV

Odds/Point Spread: Cleveland (+102) San Diego (-122)

Petco Park is the site where the San Diego Padres (5-0) will play the Cleveland Guardians (2-2) on Wednesday. The moneyline on this contest has Cleveland at +102 and San Diego is opening at -122. The total comes in at 8. The expected starting pitchers are Ben Lively and Dylan Cease.

The Guardians have hit 7 two-baggers as a team and have knocked 7 baseballs out of the park. Cleveland is slugging .485 and have struck out 24 times, while drawing a walk on 14 occasions. As a team, the Cleveland Guardians are earning 4.5 runs per game, which puts them at 15th in baseball. They have tallied 18 RBI's and 34 base knocks so far this season, while their average at the plate is .258. They have 18 runs while having a team OBP of .325.

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The Guardians have an ERA of 3.86 so far this year (14th in MLB), and their staff has rung up 24 batters. Guardians pitchers have relinquished 2 home runs and 17 total runs (13th in the league). Their pitching staff has walked 12 batters and their FIP is 3.44 as a team so far this season. Cleveland has yielded 34 hits (8.7 per 9 innings) as well as 15 earned runs. Their K/BB ratio is 2.00 and the pitching staff holds a WHIP of 1.31.

The Guardians relief pitchers have earned a save percentage of 33.3% and has stepped onto the mound in 8 save situations. The bullpen pitchers have inherited 8 base runners for the year with 37.5% of those players ended up crossing the plate. Guardians bullpen pitchers have come into the game with runners on base 6 times and also have had 9 appearances in high leverage situations. The Guardians have dispatched 15 relievers to the mound so far this season. The relief pitchers have earned 5 holds so far this year (7th in the league). They have compiled 1 save over the course of the season and have blown 2 of their 3 chances to save the game.

The Guardians have transformed 69.5% of balls hit into play into outs out of their 315 innings, which ranks them 17th in the majors. The Cincinnati Reds have a total of 105 putouts on the campaign, in addition to 31 assists and 2 errors. Their fielding percentage is currently at .986 which is 20th in baseball, and have earned 3 double plays.

Lively has taken the hill for 359 innings and has 277 punch outs during his career. Lively (21-27 career win-loss record) has a FIP of 4.47 while facing 1,538 batters during his time in the majors. His ERA is 4.54 (181 earned runs allowed) and he has a WHIP of 1.342. He has given up 369 hits (9.2 hits per 9 innings) and has had 113 free passes.

The Padres hold a slugging % of .426 and they have an average of 4.80 runs per outing (12th in baseball). They have 12 two-baggers, while walking 17 times and scoring 24 runs. San Diego has compiled 3 home runs on the year to go along with 24 runs batted in. They have been rung up on 32 occasions (20th in the league) and have notched a total of 45 base hits. The San Diego Padres hold a team OBP of .358 and a team batting average of .290 this year.

The Padres have a WHIP of 0.956 in addition to having a FIP of 3.56 as a pitching staff on the campaign. They have earned a K/BB ratio of 8.80 (44 strikeouts vs 17 walks). They rank 8th in MLB as a pitching staff in total hits surrendered with 26. They have relinquished 5 homers and they surrender 1.80 runs per 9 innings (2nd in the league). The San Diego pitching staff have given up 9 runs so far this season while having an ERA of 1.80 (9 earned runs yielded).

San Diego has called on bullpen pitchers to step onto the mound in 3 save opportunities and they have earned 3 saves. They are ranked 6th in baseball holding a save rate of 100.0%, and they have sent 19 relief pitchers onto the field for the season. Their relievers have come in 8 times in high leverage situations in addition to 4 occasions with runners on. San Diego relievers hold an inherited score rate of 0.0% out of 6 inherited runners. With 6 save situations, the Padres have compiled 3 holds and 0 blown saves.

The San Diego Padres have turned 5 double plays and have accounted for a fielding rate of .989 (15th in baseball). The Padres have recorded 43 assists, 2 errors and have a tally of 135 putouts over the course of the season. In 405 innings on the diamond, the Padres have earned a defensive efficiency of 79.1% (2nd in baseball).

Cease (57-46 win-loss record in his career) is the owner of a 3.75 earned run average while allowing 7.5 hits per nine innings. His K/BB ratio is 2.83 and he has faced 3,582 opposing hitters in his MLB career. He has given up a total of 353 earned runs while holding a WHIP of 1.253 and a FIP of 3.7. So far in his career, Cease has conceded 702 base hits while he has tallied 1,016 strikeouts in 847 innings.

Who will win tonight's MLB game against the spread or moneyline?

Tony Sink's Pick: Take San Diego (-122)

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