Chicago White Sox vs Minnesota Twins Prediction, 4/24/2025 MLB Picks, Best Bets & Odds
Game: Chicago White Sox vs Minnesota Twins
Date: Thursday, April 24, 2025
Location: Target Field in Minneapolis, MN
TV: Twins.TV
Odds/Point Spread: Chicago (+132) Minnesota (-160)
Target Field is where the Minnesota Twins (8-15) will attempt to beat the Chicago White Sox (5-18) on Thursday. The line on this matchup has Chicago at +132 while Minnesota is coming in at -160. The total comes in at 9. The starting pitchers are Shane Smith and Pablo Lopez.


As a team, the Chicago White Sox are notching 3.1 runs per game, which has them at 29th in MLB. They are sitting with 72 runs scored and have an on-base percentage of .274. The White Sox have hit 26 two-baggers as a unit and have knocked 17 baseballs out of the park. They have accrued 70 runs batted in and 149 base knocks so far this season, while their team batting average is at .201. Chicago is slugging .307 and have been rung up 196 times, while being walked on 72 occasions.
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The White Sox hold a team ERA of 4.26 so far this season (20th in baseball), and the staff has rung up 171 hitters. White Sox pitchers have yielded 29 home runs and also 102 runs (15th in MLB). Their pitching staff has walked 92 hitters and their FIP is 4.86 as a team so far this season. Chicago has allowed 176 hits (8.0 per 9 innings) as well as 94 earned runs. Their strikeout to walk ratio is 1.86 and their pitching staff holds a collective WHIP of 1.35.
The White Sox have sent 74 relief pitchers to the hill on the season. The relievers have inherited 27 base runners so far this year and 37.0% of those runners earned a run for their team. They have blown both of their save opportunities this season. The White Sox relievers have come into the game in 10 save situations. The relief pitchers have racked up 8 holds on the season (26th in the league). White Sox relief pitchers have entered the contest with runners on base 18 times as well as having 18 appearances in high leverage situations.
The Chicago Cubs have earned a total of 596 putouts over the course of the season, in addition to 196 assists and 17 errors. Their fielding percentage is holding at .979 which is 27th in the majors, and they have turned 19 double plays. The White Sox have turned 71.6% of balls in play into outs in their 1,788 innings on the diamond, ranking them 9th in MLB.
Smith has taken the hill for 22 frames and has 15 K's thus far in his career. His ERA is 2.85 (7 earned runs allowed) and his WHIP is 0.950. He has surrendered 13 hits (5.3 hits per 9 innings) with 8 free passes. Smith (0-1 career win-loss record) has earned a FIP of 2.81 while he has faced 90 hitters during his time in the majors.
The Minnesota Twins hold an OBP of .284 in addition to a batting average of .210 on the season. They have been rung up on 190 occasions (19th in the league) and have tallied 158 base hits. Minnesota has 17 long balls on the year to go along with 74 runs batted in. The Twins hold a team SLG% of .336 and they score 3.43 runs per game (26th in the league). They have recorded 38 doubles, while getting a free base 64 times as well as notching 79 runs.
The Twins have a team WHIP of 1.241 and have a FIP of 3.85 as a unit so far this season. They have earned a K/BB ratio of 8.70 (192 strikeouts vs 59 walks). They are sitting at 20th in baseball as a staff in total hits surrendered with 188. They have surrendered 25 homers and they surrender 4.39 runs per 9 innings (15th in the league). The Minnesota pitching staff have relinquished 97 runs over the course of the season and come in with a team ERA of 3.93 (87 earned runs yielded).
Minnesota relievers hold an inherited score percentage of 36.7% out of 30 inherited base runners. Their bullpen pitchers have stepped onto the mound 21 times in high leverage situations in addition to 19 occasions with base runners. Sitting with 27 save situations, the Twins have 19 holds in addition to 5 blown saves. They sit at 29th in MLB holding a save rate of 28.6%, and they have dispatched 80 bullpen pitchers to the mound on the season. Minnesota has called on relief pitchers to enter the game in 7 save opportunities and they have converted 2 saves.
In their 1,791 innings on the field, the Twins are sitting with a defensive efficiency of 68.9% (22nd in baseball). The Minnesota Twins have gotten 13 double plays and own a fielding percentage of .979 (26th in pro baseball). The Twins have recorded 156 assists, 16 errors and have accumulated 597 putouts this season.
Thus far in his career, Lopez has conceded 834 base knocks while he has accumulated 935 K's in 905 innings pitched. He has allowed 389 earned runs while holding a WHIP of 1.179 and having a FIP of 3.8. He has a K/BB ratio of 4.01 and he has gone up against 3,750 hitters during his career. Lopez (55-50 record in his career) has earned a 3.87 earned run average and has allowed 8.3 hits per 9 innings.
Who will win tonight's MLB game against the spread or moneyline?
Guy Bruhn's Pick: Take Minnesota (-160)
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Additional Resources:
Minnesota Twins - Twitter
Chicago White Sox - Twitter