Chicago White Sox vs Minnesota Twins Prediction, 4/22/2025 MLB Picks, Best Bets & Odds

Game: Chicago White Sox vs Minnesota Twins

Date: Tuesday, April 22, 2025

Location: Target Field in Minneapolis, MN

TV: Twins.TV

Odds/Point Spread: Chicago (+162) Minnesota (-196)

The Minnesota Twins (7-15) will try to beat the Chicago White Sox (5-16) at Target Field on Tuesday. The moneyline on this matchup has Chicago at +162 while Minnesota is coming in at -196. The over/under is 9. The pitchers who are expected to start are Davis Martin and Bailey Ober.

As a squad, the Chicago White Sox are putting up 3.2 runs per outing, which has them at 27th in baseball. They have accounted for 68 runs scored and have an OBP of .272. The White Sox have accounted for 23 doubles as a team and have knocked 16 baseballs out of the park. They have accounted for 66 RBI's and 134 base knocks over the course of the season, while their average at the plate comes in at .198. Chicago has a slugging rate of .306 and have been rung up 176 times, while taking a walk on 66 occasions.

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They have accumulated a K/BB ratio of 1.90 and their pitching staff holds a WHIP of 1.34. White Sox pitchers have conceded 27 long balls and 94 total runs (15th in baseball). Chicago has given up 163 base hits (8.1 per 9 innings) and 88 earned runs. The White Sox are sitting with a team ERA of 4.34 over the course of the season (23rd in the league), and the staff has rung up 156 hitters. Their pitching staff has walked 82 hitters and their FIP comes in at 4.86 as a team so far this year.

White Sox pitchers have gone to the mound with opponents on base 18 times as well as having 18 appearances in high leverage situations. The relief pitchers have notched 8 holds for the year (25th in MLB). The White Sox relief pitchers have compiled a save rate of 0.0% and have entered the game in 10 save situations. They have blown both of their save opportunities this season. The relievers have inherited 27 runners this year with 37.0% of those runners earned a run for their team. The White Sox have dispatched 71 relief pitchers to the mound on the campaign.

The White Sox have converted 71.6% of balls hit into play into outs in their 1,644 innings, which has them sitting at 10th in baseball. The Chicago Cubs have amassed 548 putouts for the season, as well as 180 assists and 15 errors. Their fielding rate sits at .980 which ranks 25th in the majors, and they have turned 16 double plays.

Martin has taken the mound for 135 frames and has 108 punch outs so far in his MLB career. His earned run average is 4.66 (70 ER's allowed) and his WHIP is 1.391. He has surrendered 140 base hits (9.3 hits per 9 innings) and has had 48 walks. Martin (4-13 career mark) is the owner of a FIP of 4.59 and he has faced 588 batters during his time in the major leagues.

Minnesota has a total of 16 long balls for the year to go along with 71 RBIs. They have 38 doubles, while taking a walk 59 times as well as putting up 75 runs. The Minnesota Twins have compiled a team OBP of .282 as well as a batting average of .211 on the year. The Twins hold a team slugging percentage of .338 and they earn 3.41 runs per contest (25th in MLB). They have been called out on strikes on 183 instances (14th in baseball) and have 153 hits.

The Minnesota pitching staff have given up 95 runs for the season while having an ERA of 4.03 (85 earned runs conceded). They have relinquished 25 long balls and they allow 4.50 runs per 9 innings (18th in the league). The Twins hold a team WHIP of 1.232 and are the owners of a FIP of 3.94 as a squad so far this season. They have earned a K/BB ratio of 8.70 (183 strikeouts against 56 bases on balls). They are sitting at 19th in baseball as a pitching staff in total hits given up with 178.

Sitting with 24 save situations, the Twins have 17 holds in addition to 5 blown saves. Minnesota has had relief pitchers enter the game in 6 save opportunities and they have come away with 1 save. Their relievers have come in 19 times in high leverage situations in addition to 19 occasions with runners on. Minnesota relievers have an inherited score percentage of 36.7% of 30 inherited base runners. They sit at 29th in the league with a save rate of 16.7%, and they have dispatched 77 bullpen pitchers onto the field this year.

The Minnesota Twins have turned 11 double plays and have a fielding rate of .978 (27th in baseball). The Twins have 149 assists, 16 errors and have a tally of 570 putouts for the season. In their 1,710 innings on the diamond, the Twins hold a efficiency on defense of 69.3% (22nd in MLB).

Ober (26-22 career win-loss mark) has a 3.86 earned run average while allowing 7.7 hits per nine innings. His K/BB ratio is 4.64 and he has faced 1,977 batters during his career. He has given up 210 ER's while earning a WHIP of 1.081 and a FIP of 3.8. During his pro baseball career, Ober has conceded 422 hits while he has totaled 501 strikeouts in 490 innings.

Who will win tonight's MLB game against the spread or moneyline?

Josh Schonwald's Pick: Take Chicago (+162)

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