Chicago White Sox vs Cleveland Guardians Prediction, 4/8/2025 MLB Picks, Best Bets & Odds
Game: Chicago White Sox vs Cleveland Guardians
Date: Tuesday, April 8, 2025
Location: Progressive Field in Cleveland, OH
TV: CLEGuardians.TV
Odds/Point Spread: Chicago (+220) Cleveland (-275)
The Chicago White Sox (2-7) are on their way to Progressive Field on Tuesday where they will take on the Cleveland Guardians (3-6). The moneyline on this contest has Chicago at +220 and Cleveland is sitting at -275. The total has been set at 8. The pitchers taking the mound will be Shane Smith and Ben Lively.


As a squad, the Chicago White Sox are scoring 3.6 runs per game, which has them sitting at 23rd in the league. They have a total of 32 runs scored and have an on-base percentage of .273. The White Sox have accounted for 11 two-baggers as a team and have hit 9 baseballs out of the stadium. They have earned 31 RBI's as well as 60 hits so far this year, while their batting average sits at .211. Chicago has a slugging % of .344 and have struck out 66 times, while drawing a walk on 25 occasions.
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They have accrued a K/BB ratio of 1.97 and their pitching staff has earned a collective WHIP of 1.29. White Sox pitchers have surrendered 10 home runs and 37 runs in total (11th in the league). Chicago has surrendered 66 base knocks (7.6 per 9 innings) and also 35 earned runs. The White Sox have a team earned run average of 4.02 on the season (12th in MLB), and their staff has rung up 69 batters. They have walked 35 opposing players and their FIP sits at 4.63 as a team on the season.
White Sox relief pitchers have come into the game with opponents on base 9 times and also have had 10 appearances in high leverage situations. The relief pitchers have a total of 7 holds on the campaign (10th in the league). The White Sox relievers haven't earned a save in 9 opportunities. They have no saves on the season and have blown 2 of 2 chances to save the game. The relievers have inherited 17 base runners this year and 41.2% of those players crossed home plate. The White Sox have dispatched 31 relief pitchers to the hill for the season.
The Chicago Cubs are sitting with 235 putouts this year, as well as 81 assists and 4 errors. Their fielding percentage is at .988 which puts them in 12th in baseball, and they have turned 9 double plays. The White Sox have turned 72.6% of balls hit into play into outs out of their 705 innings, which has them ranked 9th in the majors.
Smith (0-0 record in his career) has a FIP of 3.41 and he has gone up against 22 opposing hitters in the majors. He has surrendered 2 hits (3.5 hits per nine innings) and has had 4 walks. His ERA is 3.46 (2 ER's allowed) and his WHIP is 1.154. Smith has taken the hill for 5 innings and has racked up 3 strikeouts thus far in his career.
Cleveland has accumulated 13 HRs for the year as well as 34 runs batted in. They have 11 doubles, while taking a walk 32 times and putting up 34 runs. The Cleveland Guardians have accumulated an on-base percentage of .300 in addition to a team batting average of .221 this year. The Guardians hold a team slugging % of .400 and they score 3.78 runs per outing (18th in MLB). They have struck out on 77 occasions (18th in baseball) and have 64 hits.
The Cleveland pitching staff have surrendered 51 runs so far this season while holding an ERA of 5.09 (43 earned runs surrendered). They have surrendered 14 HR's and they concede 6.04 runs per 9 innings (27th in the league). The Guardians hold a team WHIP of 1.539 and have a FIP of 5.32 as a unit on the campaign. They currently have a strikeout to walk ratio of 7.10 (60 strikeouts vs 31 bases on balls). They are currently ranked 22nd in the league as a staff in total hits relinquished with 86.
Sitting with 11 save situations, the Guardians have 8 holds and also 2 blown saves. Cleveland has called on relievers to enter the contest in 3 save chances and they have come away with 1 save. Their bullpen pitchers have come in 9 times in high leverage situations in addition to 10 occasions with runners on base. Cleveland relievers hold an inherited score rate of 26.7% out of their 15 inherited base runners. They are currently ranked 25th in baseball holding a save rate of 33.3%, and they have dispatched 32 relievers onto the field on the season.
The Cleveland Guardians have gotten 7 double plays and have a fielding rate of .970 (30th in professional baseball). The Guardians have recorded 66 assists, 9 errors and have earned 228 putouts so far this year. In 684 innings played, the Guardians have earned a efficiency on defense of 66.8% (24th in pro baseball).
Lively (21-28 career win-loss record) is the owner of a 4.59 ERA while surrendering 9.3 hits per nine innings. He has a strikeout to walk ratio of 2.47 and he has gone up against 1,578 opposing batters during his MLB career. He has allowed a total of 188 ER's while earning a WHIP of 1.344 and a FIP of 4.5. During his MLB career, Lively has given up 380 base hits while he has earned 284 K's in 368 innings pitched.
Who will win tonight's MLB game against the spread or moneyline?
Josh Schonwald's Pick: Take Cleveland (-275)
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Additional Resources:
Cleveland Guardians - Twitter
Chicago White Sox - Twitter