Chicago White Sox vs Cleveland Guardians Prediction, 4/10/2025 MLB Picks, Best Bets & Odds

Game: Chicago White Sox vs Cleveland Guardians

Date: Thursday, April 10, 2025

Location: Progressive Field in Cleveland, OH

TV: CLEGuardians.TV

Odds/Point Spread: Chicago (+162) Cleveland (-196)

The Chicago White Sox (2-8) are headed to Progressive Field on Thursday where they will meet the Cleveland Guardians (4-6). The moneyline on this matchup has Chicago at +162 while Cleveland is sitting at -196. The total is set at 9. The pitchers who are expected to start will be Jonathan Cannon and Gavin Williams.

The White Sox have tallied 11 two-baggers as a squad and have knocked 9 baseballs out of the park. Chicago is slugging .321 and have struck out 75 times, while being walked on 30 occasions. As a team, the Chicago White Sox are putting up 3.2 runs per game, which has them sitting at 26th in the league. They have recorded 31 runs batted in in addition to 62 base knocks over the course of the season, and their team batting average comes in at .199. They have accounted for 32 runs while having a team on-base percentage of .268.

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They have a K/BB ratio of 1.95 and the pitching staff holds a collective WHIP of 1.27. White Sox pitchers have conceded 10 home runs and 38 runs (5th in the league). Chicago has conceded 69 hits (7.2 per 9 innings) and 36 earned runs. The White Sox are sitting with a team earned run average of 3.75 for the year (13th in the league), and they have struck out 78 hitters. Their pitching staff has walked 40 opposing hitters and their FIP sits at 4.47 as a squad on the campaign.

The White Sox bullpen have a save percentage of 0.0% and has stepped onto the mound in 9 save situations. The relief pitchers have inherited 17 runners this season and 41.2% of them earned a run for their team. White Sox relief pitchers have stepped onto the hill with opponents on base 9 times as well as having 11 appearances in high leverage situations. The White Sox have dispatched 33 relief pitchers to the hill so far this year. The bullpen have recorded 7 holds on the campaign (13th in baseball). They have recorded no saves this season and have blown 2 of 2 chances to save the game.

The Chicago Cubs are sitting with 259 putouts for the season, in addition to 87 assists and 4 errors. Their fielding percentage is currently at .989 which is 10th in professional baseball, and have 9 double plays. The White Sox have transformed 73.4% of baseballs in play into outs out of 777 innings, which has them sitting 6th in MLB.

Cannon has taken the mound for 132 innings and has accumulated 99 K's during his career. Cannon (5-11 career mark) has a FIP of 4.36 and he has gone up against 561 batters in the major leagues. His earned run average is 4.42 (65 earned runs allowed) and he has a career WHIP of 1.345. He has conceded 132 base knocks (9.0 hits per nine innings) and has 46 walks.

The Cleveland Guardians hold an on-base percentage of .298 in addition to a batting average of .211 over the course of the season. They have been rung up on 86 instances (22nd in the league) and have accounted for 67 base hits. Cleveland has tallied 13 home runs over the course of the season to go along with 35 runs batted in. The Guardians hold a team slugging percentage of .375 and they average 3.50 runs per contest (22nd in the league). They have notched 11 doubles, while taking a walk 37 times and putting up 35 runs.

The Guardians have a team WHIP of 1.459 in addition to having a FIP of 5.03 as a pitching staff on the year. They rank 17th in the league as a staff in total hits surrendered with 88. The Cleveland pitching staff have conceded 51 runs this season while having an ERA of 4.55 (43 earned runs relinquished). Their K/BB ratio sits at 7.30 (69 strikeouts vs 36 free passes). They have surrendered 14 homers and they relinquish 5.40 runs per 9 innings (27th in the league).

Sitting with 11 save situations, the Guardians have tallied 8 holds and 2 blown saves. Cleveland has called on bullpen pitchers to step onto the mound in 3 save opportunities and they have recorded 1 save. Their bullpen pitchers have come in 12 times in high leverage situations and also on 10 occasions with runners on. Cleveland bullpen pitchers have an inherited score percentage of 26.7% of 15 inherited base runners. They sit at 27th in baseball with a save percentage of 33.3%, and they have sent 36 relief pitchers onto the field this year.

In 765 innings on the field, the Guardians are sitting with a efficiency on defense of 68.1% (23rd in professional baseball). The Cleveland Guardians have gotten 9 double plays and own a fielding percentage of .971 (30th in professional baseball). The Guardians have racked up 75 assists, 10 errors and have earned a total of 255 putouts on the campaign.

In his career, Williams has given up 147 base hits while earning 167 K's in 166 frames. He has allowed a total of 75 ER's while earning a WHIP of 1.325 and being the owner of a FIP of 4.0. He has a K/BB ratio of 2.29 and he has faced 714 batters so far in his MLB career. Williams (6-15 career win-loss record) has a 4.07 ERA and has allowed 8.0 hits per nine innings.

Who will win tonight's MLB game against the spread or moneyline?

Guy Bruhn's Pick: Take Cleveland (-196)

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