Chicago White Sox vs Boston Red Sox Prediction, 4/20/2025 MLB Picks, Best Bets & Odds

Game: Chicago White Sox vs Boston Red Sox

Date: Sunday, April 20, 2025

Location: Fenway Park in Boston, MA

TV: NESN

Odds/Point Spread: Chicago (+132) Boston (-160)

Fenway Park is the location where the Boston Red Sox (10-10) will compete against the Chicago White Sox (4-14) on Sunday. The odds on this game have Chicago at +132 and Boston is opening at -160. The over/under has been set at 8.5. The pitchers taking the mound are Sean Burke and Tanner Houck.

The White Sox have tallied 19 two-baggers as a team and have hit 12 baseballs out of the stadium. Chicago has a slugging percentage of .296 and have struck out 150 times, while taking a walk on 58 occasions. As a team, the Chicago White Sox are compiling 3.0 runs per outing, which has them at 28th in MLB. They have 52 runs batted in and 112 hits for the year, while their average at the plate is .196. They have a total of 54 runs scored and have an on-base percentage of .270.

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The White Sox have compiled a team ERA of 4.26 on the year (22nd in baseball), and their staff has struck out 136 hitters. White Sox pitchers have allowed 21 home runs and 76 total runs (10th in baseball). Their pitching staff has walked 67 opposing players and their FIP sits at 4.52 as a team so far this year. Chicago has given up 139 hits (8.0 per 9 innings) as well as 74 earned runs. Their K/BB ratio is 2.03 and the pitching staff has recorded a WHIP of 1.32.

The White Sox have sent 59 relief pitchers to the mound so far this season. The relief pitchers have inherited 26 base runners on the season and 38.5% of them crossed the plate. They have blown both of their save opportunities. The White Sox bullpen have earned a save rate of 0.0% and have entered the game in 9 save situations. The relief pitchers have notched 7 holds so far this season (26th in the league). White Sox bullpen pitchers have entered the game with runners on 16 times in addition to having 13 appearances in high leverage situations.

The White Sox have turned 71.4% of balls in play into outs out of 1,407 innings, which has them sitting at 11th in MLB. The Chicago Cubs have a tally of 469 putouts at this point in the season, in addition to 157 assists and 11 errors. Their fielding percentage is at .983 which ranks 22nd in the majors, and have earned 15 double plays.

Burke has taken the mound for 35 innings and is sitting with 32 strikeouts during his pro baseball career. His earned run average is 4.35 (17 ER's allowed) and his career WHIP is 1.250. He has surrendered 31 base knocks (7.9 hits per nine innings) and has 13 walks. Burke (3-3 career win-loss record) is the owner of a FIP of 4.28 and he has faced 153 opposing batters during his time in the majors.

The Boston Red Sox have recorded a team OBP of .320 as well as a team batting average of .247 so far this year. They have been called out on strikes on 197 occasions (1st in MLB) and are sitting with 171 hits. Boston has knocked in 17 HRs for the season as well as 82 RBIs. The Red Sox have a slugging percentage of .382 and they are earning 4.30 runs per contest (14th in baseball). They have put up 38 doubles, while taking a walk 71 times as well as putting up 86 runs.

The Boston pitching staff have given up 97 runs on the campaign while holding an ERA of 4.17 (82 earned runs relinquished). They have yielded 16 homers and they concede 4.93 runs per 9 innings (25th in the league). The Red Sox have a WHIP of 1.327 and are the owners of a FIP of 3.41 as a staff so far this year. Their K/BB ratio sits at 8.40 (166 strikeouts vs 58 walks). They are sitting at 29th in MLB as a staff in total hits given up with 177.

Sitting with 15 save situations, the Red Sox have 5 holds in addition to 3 blown saves. Boston has called on relievers to step onto the hill in 10 save chances and they have tallied 7 saves. Their relief pitchers have come in 21 times in high leverage situations in addition to 18 occasions with base runners. Boston relievers have an inherited score percentage of 50.0% of 24 inherited runners. They are currently ranked 9th in MLB with a save percentage of 70.0%, and they have dispatched 62 relievers onto the field on the year.

The Boston Red Sox have gotten 23 double plays and have earned a fielding percentage of .973 (30th in the majors). The Red Sox have accrued 183 assists, 20 errors and have accounted for 532 putouts for the season. In 1,596 innings played, the Red Sox hold a efficiency on defense of 65.7% (30th in MLB).

So far in his pro baseball career, Houck has surrendered 399 base hits while he has totaled 428 punch outs in 448 innings. Houck (24-31 career mark) holds a 3.79 earned run average while surrendering 8.0 hits per 9 innings. He has allowed 189 earned runs while holding a WHIP of 1.224 and a FIP of 3.7. His K/BB ratio is 2.85 and he has gone up against 1,888 opposing batters in his MLB career.

Who will win tonight's MLB game against the spread or moneyline?

Tony Sink's Pick: Take Chicago (+132)

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