Chicago Cubs vs San Diego Padres Prediction, 4/15/2025 MLB Picks, Best Bets & Odds

Game: Chicago Cubs vs San Diego Padres

Date: Tuesday, April 15, 2025

Location: Petco Park in San Diego, CA

TV: Padres.TV

Odds/Point Spread: Chicago (+172) San Diego (-210)

The San Diego Padres (13-3) will play the Chicago Cubs (11-7) at Petco Park on Tuesday. The line on this matchup has Chicago at +172 and San Diego is priced at -210. The over/under has been set at 8.5. The pitchers who are expected to start are Shota Imanaga and Randy Vasquez.

As a team, the Chicago Cubs are notching 6.4 runs per outing, which has them at 1st in MLB. They have earned 116 runs while having a team OBP of .348. The Cubs have hit 32 two-baggers as a team and have hit 25 baseballs out of the park. They have 113 RBI's in addition to 161 hits this year, while their batting average sits at .256. Chicago has a slugging % of .439 and have been rung up 145 times, while drawing a walk on 83 occasions.

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They have accumulated a K/BB ratio of 2.32 and their pitching staff holds a WHIP of 1.35. Cubs pitchers have given up 19 home runs and 73 runs in total (20th in MLB). Chicago has yielded 155 hits (8.8 per 9 innings) in addition to 71 earned runs. The Cubs have compiled a team ERA of 4.02 on the campaign (18th in MLB), and they have rung up 137 batters. Their pitching staff has walked 59 opposing players and their FIP sits at 4.06 as a team for the year.

Cubs pitchers have entered the contest with opponents on base 9 times as well as having 12 appearances in high leverage situations. The bullpen have accumulated 13 holds for the year (6th in the league). The Cubs relief pitchers have accumulated a save percentage of 55.6% and has come into the game in 22 save situations. They have compiled 5 saves for the year and have blown 4 of 9 save chances. The relief pitchers have inherited 12 base runners for the season with 33.3% of those runners ended up crossing the plate. The Cubs have sent 56 relief pitchers to the mound this season.

The Cubs have transformed 69.6% of balls hit into play into outs out of 1,431 innings, ranking them 21st in professional baseball. The Boston Red Sox have accumulated 477 putouts on the year, in addition to 149 assists and 6 errors. Their fielding rate is currently at .991 which puts them in 4th in MLB, and they have turned 13 double plays.

Imanaga has thrown 196 innings and has racked up 188 K's in his career. Imanaga (17-4 career record) is the owner of a FIP of 2.85 and he has gone up against 785 batters during his time in the major leagues. His ERA is 2.89 (63 ER's allowed) and his career WHIP is 1.009. He has allowed 163 hits (7.5 hits per 9 innings) and has had 35 free passes.

San Diego has accumulated 15 home runs so far this year to go along with 66 RBIs. They have notched 28 doubles, while getting a free base 52 times and putting up 73 runs. The San Diego Padres are sitting with a team on-base percentage of .348 in addition to a batting average of .283 on the year. The Padres have a team SLG% of .423 and they tally 4.56 runs per contest (10th in the league). They have been called out on strikes on 103 occasions (30th in the league) and have tallied 148 hits.

The San Diego pitching staff have yielded 43 runs over the course of the season while holding an ERA of 2.68 (42 earned runs relinquished). They have surrendered 11 dingers and they surrender 2.74 runs per 9 innings (1st in MLB). The Padres have a team WHIP of 1.043 in addition to having a FIP of 3.34 as a team this year. They currently have a K/BB ratio of 8.90 (139 strikeouts against 57 bases on balls). They are currently ranked 1st in the league as a pitching staff in total hits conceded with 90.

San Diego has had bullpen pitchers enter the contest in 8 save chances and they have come away with 8 saves. They rank 3rd in baseball holding a save rate of 100.0%, and they have sent 53 relief pitchers to the hill for the year. Their relievers have stepped onto the mound 21 times in high leverage situations in addition to 11 occasions with runners on. San Diego relievers hold an inherited score rate of 27.8% of 18 inherited base runners. With 22 save situations, the Padres have amassed 14 holds and also no blown saves.

The San Diego Padres have turned 13 double plays and have notched a fielding percentage of .987 (8th in baseball). The Padres have recorded 117 assists, 7 errors and have accumulated 423 putouts so far this season. In 1,269 innings played, the Padres have a efficiency on defense of 76.2% (2nd in professional baseball).

Vasquez (7-10 win-loss mark in his career) has earned a 4.07 ERA and has surrendered 9.3 hits per nine innings. He has a strikeout to walk ratio of 1.71 and he has faced 659 hitters during his career. He has surrendered 68 ER's while holding a WHIP of 1.430 and being the owner of a FIP of 4.0. In his career, Vasquez has given up 156 hits while accumulating 101 strikeouts in 150 innings.

Who will win tonight's MLB game against the spread or moneyline?

Tony Sink's Pick: Take Chicago (+172)

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