Chicago Cubs vs Arizona Diamondbacks Prediction, 3/29/2025 MLB Picks, Best Bets & Odds
Game: Chicago Cubs vs Arizona Diamondbacks
Date: Saturday, March 29, 2025
Location: Chase Field in Phoenix, AZ
TV: DBACKS.TV
Odds/Point Spread: Chicago (+125) Arizona (-145)
The Arizona Diamondbacks (89-73 last season) are hosting the Chicago Cubs (83-79 last year) at Chase Field on Saturday. The moneyline on this matchup has Chicago at +125 while Arizona is coming in at -145. The over/under is 9. The pitchers taking the mound are Shota Imanaga and Brandon Pfaadt.


Chicago had a slugging percentage of .393 and struck out 1,362 times, while drawing a walk on 546 occasions. They amassed 696 RBI's in addition to 1,318 hits during the previous year, and their average at the plate came in at .242. The Cubs hit 253 two-baggers as a squad and smacked 170 baseballs out of the stadium. They had a total of 736 runs while having a team on-base percentage of .317. As a unit, the Chicago Cubs scored 4.5 runs per game, which put them at 12th in baseball.
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Their strikeout to walk ratio was at 2.78 and their pitching staff had a collective WHIP of 1.25. Cubs pitchers gave up 181 long balls and also 669 total runs (10th in baseball). Chicago surrendered 1,302 hits (8.2 per 9 innings) and also 602 earned runs. The Cubs had a team earned run average of 3.78 over the course of the prior season (10th in MLB), and their staff rung up 1,348 hitters. They walked 485 opposing batters and their FIP was 4.04 as a team over the course of last season.
The Cubs had dispatched 496 relievers to the mound over the course of the prior season. The relievers inherited 217 runners for the previous season with 31.8% of them ended up crossing the plate. They recorded 38 saves over the course of the prior season and missed out on 26 out of their 64 save opportunities. The Cubs relief pitchers had a save rate of 59.4% and came into the game in 145 save situations. The relievers had 80 holds last season (21st in the league). Cubs bullpen pitchers entered the game with players on base 141 times and also had 170 games in high leverage situations.
The Cubs turned 70.5% of balls hit into play into outs out of 12,891 innings on the field, which ranked them 8th in pro baseball. The Chicago Cubs notched a total of 4,297 putouts over the course of the prior season, as well as 1,349 assists and 76 errors. Their fielding percentage held steady at .987 which had them ranked 7th in professional baseball, and accumulated 91 double plays.
Imanaga (15-3 win-loss record in his career) holds a FIP of 2.87 while going up against 694 opposing batters during his time in the major leagues. He has surrendered 149 base knocks (7.7 hits per 9 innings) with 28 walks. His earned run average is 2.91 (56 ER's allowed) and he has a career WHIP of 1.023. Imanaga has thrown 173 innings and has accounted for 174 punch outs thus far in his career.
Arizona hit 211 home runs in the prior season in addition to 845 runs batted in. They hit 271 doubles, while taking a walk 569 times as well as earning 886 runs. The Arizona Diamondbacks recorded a team on-base percentage of .337 as well as a team batting average of .263 last season. The Diamondbacks held a slugging percentage of .440 and they were earning 5.47 runs per game (1st in MLB). They struck out on 1,265 occasions (24th in MLB) and earned a total of 1,452 base hits.
The Diamondbacks had a WHIP of 1.351 in addition to having a FIP of 4.09 as a staff last year. They were ranked 29th in the league as a staff in total hits relinquished with 1,468. The Arizona pitching staff relinquished 788 runs for the previous season while holding an ERA of 4.62 (741 earned runs relinquished). Their K/BB ratio was 8.20 (1,313 strikeouts vs 481 bases on balls). They gave up 181 home runs and they surrendered 4.91 runs per 9 innings (26th in the league).
Ending the season with 153 save situations, the Diamondbacks amassed 87 holds and also 26 blown saves. Arizona had relief pitchers enter the contest in 64 save opportunities and they walked away with 38 saves. Their relievers stepped onto the mound 168 times in high leverage situations in addition to 152 occasions with runners on. Arizona relievers held an inherited score rate of 39.0% out of their 218 inherited runners. They ranked 25th in baseball with a save percentage of 59.4%, and they sent 536 relievers to the mound last season.
In their 12,990 innings played, the Diamondbacks earned a defensive efficiency of 68.2% (27th in professional baseball). The Arizona Diamondbacks had 138 double plays and held a fielding percentage of .989 (1st in professional baseball). The Diamondbacks racked up 1,456 assists, 62 errors and are sitting with 4,330 putouts for the previous season.
Thus far in his career, Pfaadt has allowed 292 hits while earning 279 strikeouts in 277 innings pitched. Pfaadt (14-19 mark in his career) holds a 5.06 ERA and has allowed 9.5 hits per nine innings. He has given up 156 earned runs while earning a WHIP of 1.299 and having a FIP of 5.0. He has a strikeout to walk ratio of 4.10 and he has faced 1,181 batters in his MLB career.
Who will win tonight's MLB game against the spread or moneyline?
Parlay's Pundit's Pick: Take Arizona (-145) and under 9 runs
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Additional Resources:
Arizona Diamondbacks - Twitter
Chicago Cubs - Twitter