Boston Red Sox vs Cleveland Guardians Prediction, 4/26/2025 MLB Picks, Best Bets & Odds
Game: Boston Red Sox vs Cleveland Guardians
Date: Saturday, April 26, 2025
Location: Progressive Field in Cleveland, OH
TV: CLEGuardians.TV
Odds/Point Spread: Boston (+132) Cleveland (-160)
Progressive Field is the location where the Cleveland Guardians (14-10) will take on the Boston Red Sox (14-12) on Saturday. The moneyline on this matchup has Boston at +132 while Cleveland is at -160. The over/under comes in at 9. The pitchers who are expected to start are Walker Buehler and Logan Allen.


Boston has a slugging % of .399 and have been called out on strikes 245 times, while drawing a walk on 101 occasions. They have earned 116 RBI's in addition to 221 hits on the year, while their batting average is at .247. The Red Sox have earned 51 doubles as a unit and have knocked 26 baseballs out of the stadium. They are sitting with 121 runs while holding a team OBP of .328. As a squad, the Boston Red Sox are putting up 4.7 runs per game, which ranks them 8th in baseball.
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The Red Sox are sitting with a team earned run average of 4.07 on the year (17th in the league), and the staff has rung up 220 hitters. Red Sox pitchers have allowed 23 home runs and also 124 runs in total (28th in the league). Their pitching staff has walked 80 players from the other team and their FIP is 3.62 as a team on the campaign. Boston has surrendered 223 base hits (8.6 per 9 innings) in addition to 105 earned runs. They have accrued a K/BB ratio of 2.75 and the pitching staff has a team WHIP of 1.31.
Red Sox pitchers have entered the contest with runners on base 21 times in addition to having 27 appearances in high leverage situations. The relievers have recorded 9 holds on the season (25th in the league). The Red Sox bullpen have recorded a save percentage of 61.5% and have come into the game in 23 save situations. They have earned 8 saves on the campaign and have blown 5 of 13 save opportunities. The bullpen pitchers have inherited 28 runners on the campaign with 53.6% of those runners crossed the plate. The Red Sox have dispatched 80 relievers to the mound for the year.
The Red Sox have converted 66.8% of balls hit into play into outs in their 2,091 innings on the field, which has them sitting at 29th in baseball. The Baltimore Orioles have a total of 697 putouts this season, in addition to 243 assists and 27 errors. Their fielding percentage is at .972 which is 30th in MLB, and have 26 double plays.
Buehler has taken the mound for 740 frames and has accounted for 780 punch outs in his career. Buehler (50-23 win-loss record in his career) sits with a FIP of 3.26 while facing 3,017 batters in the major leagues. His earned run average is 3.31 (272 earned runs allowed) and he has a WHIP of 1.095. He has given up 613 hits (7.5 hits per nine innings) and has 198 free passes.
The Cleveland Guardians have accounted for an OBP of .306 and a team batting average of .235 on the campaign. They have struck out on 188 occasions (23rd in baseball) and have totaled 183 base hits. Cleveland has knocked in 28 home runs on the campaign to go along with 90 runs batted in. The Guardians hold a team slugging % of .386 and they are scoring 4.00 runs per contest (20th in MLB). They have hit 30 two-baggers, while getting a free base 78 times as well as scoring 96 runs.
The Guardians hold a team WHIP of 1.376 in addition to having a FIP of 4.16 as a squad for the year. Their strikeout to walk ratio is 9.10 (212 strikeouts vs 90 walks). They are sitting at 21st in MLB as a staff in total hits conceded with 199. They have relinquished 29 dingers and they relinquish 4.33 runs per 9 innings (13th in the league). The Cleveland pitching staff have conceded 101 runs this season while holding an ERA of 3.94 (92 earned runs surrendered).
Cleveland has called on relief pitchers to step onto the mound in 11 save opportunities and they have tallied 8 saves. They rank 7th in MLB with a save percentage of 72.7%, and they have sent 84 bullpen pitchers onto the diamond for the year. Their bullpen pitchers have come in 21 times in high leverage situations and also on 22 occasions with runners on base. Cleveland relief pitchers hold an inherited score percentage of 13.3% out of 30 inherited base runners. With 37 save situations, the Guardians have accumulated 26 holds in addition to 3 blown saves.
The Cleveland Guardians have gotten 24 double plays and have notched a fielding percentage of .983 (21st in baseball). The Guardians have recorded 184 assists, 14 errors and have 630 putouts for the season. In 1,890 innings played, the Guardians have a defensive efficiency of 68.1% (24th in the majors).
During his pro baseball career, Allen has surrendered 258 base knocks and he has 214 strikeouts in 243 frames. Allen (16-14 career record) holds a 4.44 earned run average while giving up 9.5 hits per 9 innings. He has surrendered a total of 120 ER's while holding a WHIP of 1.467 and having a FIP of 4.4. He has a K/BB ratio of 2.16 and he has faced 1,059 batters in his career.
Who will win tonight's MLB game against the spread or moneyline?
Tony Sink's Pick: Take Boston (+132)
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Additional Resources:
Cleveland Guardians - Twitter
Boston Red Sox - Twitter