Boston Red Sox vs Cleveland Guardians Prediction, 4/25/2025 MLB Picks, Best Bets & Odds

Game: Boston Red Sox vs Cleveland Guardians

Date: Friday, April 25, 2025

Location: Progressive Field in Cleveland, OH

TV: CLEGuardians.TV

Odds/Point Spread: Boston (+102) Cleveland (-122)

Progressive Field is where the Cleveland Guardians (14-10) will try to defeat the Boston Red Sox (14-12) on Friday. The line on this contest has Boston at +102 and Cleveland is coming in at -122. The over/under is set at 8.5. The pitchers who are expected to start are Tanner Houck and Ben Lively.

Boston has a slugging percentage of .399 and have been rung up 245 times, while taking a walk on 101 occasions. They have accumulated 116 runs batted in and 221 base knocks for the season, while their batting average comes in at .247. The Red Sox have hit 51 doubles as a squad and have knocked 26 balls out of the park. They have tallied 121 runs scored and have an on-base percentage of .328. As a team, the Boston Red Sox are knocking in 4.7 runs per game, which puts them at 8th in MLB.

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Their K/BB ratio is 2.75 and the pitching staff sits with a WHIP of 1.31. Red Sox pitchers have surrendered 23 home runs in addition to 124 runs (28th in MLB). Boston has surrendered 223 base hits (8.6 per 9 innings) in addition to 105 earned runs. The Red Sox have an ERA of 4.07 on the campaign (17th in baseball), and the staff has struck out 220 hitters. Their pitching staff has walked 80 hitters and their FIP sits at 3.62 as a squad on the campaign.

Red Sox pitchers have gone to the mound with players on base 21 times as well as having 27 appearances in high leverage situations. The relief pitchers have earned 9 holds for the season (25th in MLB). The Red Sox bullpen have compiled a save rate of 61.5% and have stepped onto the mound in 23 save situations. They have earned 8 saves on the year and have blown 5 of their 13 chances to save the game. The bullpen pitchers have inherited 28 base runners for the season with 53.6% of them crossed home plate. The Red Sox have dispatched 80 relievers to the hill on the season.

The Red Sox have converted 66.8% of balls hit into play into outs in their 2,091 innings, which has them ranked 29th in MLB. The Baltimore Orioles have earned a total of 697 putouts on the campaign, in addition to 243 assists and 27 errors. Their fielding percentage is currently at .972 which is 30th in baseball, and have 26 double plays.

Houck has taken the ball for 454 innings and has accounted for 435 punch outs thus far in his career. His ERA is 3.78 (191 ER's allowed) and his WHIP is 1.219. He has given up 402 base hits (8.0 hits per 9 innings) and has had 152 free passes. Houck (24-31 win-loss mark in his career) has a FIP of 3.73 while he has faced 1,911 opposing hitters in the major leagues.

The Cleveland Guardians hold an on-base percentage of .306 in addition to a team batting average of .235 so far this year. They have struck out on 188 occasions (23rd in the league) and have a total of 183 hits. Cleveland has tallied 28 home runs this season as well as 90 runs batted in. The Guardians hold a slugging % of .386 and they average 4.00 runs per game (20th in the league). They have 30 doubles, while taking a walk 78 times as well as putting up 96 runs.

The Cleveland pitching staff have allowed 101 runs for the season while holding an ERA of 3.94 (92 earned runs relinquished). They have yielded 29 homers and they give up 4.33 runs per 9 innings (13th in the league). The Guardians have a WHIP of 1.376 and have a FIP of 4.16 as a unit this year. They have earned a strikeout to walk ratio of 9.10 (212 strikeouts against 90 free passes). They are sitting at 21st in baseball as a pitching staff in total hits surrendered with 199.

Cleveland bullpen pitchers have an inherited score percentage of 13.3% out of their 30 inherited runners. Their relief pitchers have stepped onto the hill 21 times in high leverage situations and on 22 occasions with base runners. With 37 save situations, the Guardians have 26 holds and 3 blown saves. They rank 7th in the league holding a save percentage of 72.7%, and they have dispatched 84 bullpen pitchers to the hill so far this season. Cleveland has called on relievers to enter the contest in 11 save chances and they have recorded 8 saves.

The Cleveland Guardians have gotten 24 double plays and have a fielding rate of .983 (21st in pro baseball). The Guardians have 184 assists, 14 errors and have accumulated 630 putouts for the year. Out of their 1,890 innings on the field, the Guardians are sitting with a efficiency on defense of 68.1% (24th in MLB).

So far in his pro baseball career, Lively has allowed 393 hits while he has earned 296 strikeouts in 384 innings. He has conceded a total of 192 ER's while holding a WHIP of 1.337 and a FIP of 4.4. His K/BB ratio is 2.45 and he has gone up against 1,640 hitters in his career. Lively (22-29 win-loss record in his career) has a 4.50 earned run average while giving up 9.2 hits per nine innings.

Who will win tonight's MLB game against the spread or moneyline?

Tony Sink's Pick: Take Boston (+102)

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