Arizona Diamondbacks vs Chicago Cubs Prediction, 4/20/2025 MLB Picks, Best Bets & Odds
Game: Arizona Diamondbacks vs Chicago Cubs
Date: Sunday, April 20, 2025
Location: Wrigley Field in Chicago, IL
TV: Marquee
Odds/Point Spread: Arizona (-275) Chicago (+220)
The Arizona Diamondbacks (12-7) are en route to Wrigley Field on Sunday where they will compete against the Chicago Cubs (12-9). The line on this matchup has Arizona at -275 and Chicago is coming in at +220. The over/under comes in at 8.5. The starting pitchers will be Merrill Kelly and Jameson Taillon.


As a unit, the Arizona Diamondbacks are earning 5.5 runs per game, which is 3rd in the league. They have earned a total of 104 runs while holding a team on-base percentage of .347. The Diamondbacks have accumulated 39 two-baggers as a squad and have knocked 26 baseballs out of the park. They have earned 102 RBI's and 158 hits so far this year, and their team batting average sits at .254. Arizona is slugging .452 and have been called out on strikes 139 times, while drawing a walk on 86 occasions.
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The Diamondbacks have an ERA of 4.07 so far this year (16th in MLB), and they have rung up 173 batters. Diamondbacks pitchers have surrendered 20 long balls and 82 runs (16th in baseball). They have walked 57 opposing batters and their FIP comes in at 3.66 as a unit this season. Arizona has surrendered 144 hits (7.7 per 9 innings) as well as 76 earned runs. They have accumulated a K/BB ratio of 3.04 and the pitching staff has earned a collective WHIP of 1.20.
The Diamondbacks relievers have accumulated a save percentage of 100.0% and have stepped onto the mound in 17 save situations. The relief pitchers have inherited 16 base runners on the campaign with 25.0% of those runners crossed the plate. Diamondbacks relief pitchers have entered the game with opponents on base 12 times in addition to having 12 appearances in high leverage situations. The Diamondbacks have sent 54 relief pitchers to the mound for the season. The bullpen have tallied 11 holds for the year (21st in the league). They have earned 6 saves so far this year and haven't missed an opportunity.
The Diamondbacks have turned 70.6% of balls hit into play into outs out of their 1,512 innings on the field, ranking them 15th in MLB. The Arizona Diamondbacks have a tally of 504 putouts this season, in addition to 167 assists and 11 errors. Their fielding percentage is holding at .984 which is 18th in the majors, and have a total of 9 double plays.
Kelly has taken the mound for 845 innings and is sitting with 760 K's so far in his pro baseball career. His earned run average is 3.87 (363 earned runs allowed) and he has a WHIP of 1.219. He has conceded 768 base hits (8.2 hits per 9 innings) and has 262 walks. Kelly (56-45 win-loss mark in his career) has earned a FIP of 3.81 and he has gone up against 3,487 opposing hitters during his time in the majors.
The Cubs have a SLG% of .431 and they score 5.90 runs per game (2nd in the league). They have recorded 39 two-baggers, while walking 90 times and earning 124 runs. Chicago has tallied 27 HRs so far this year as well as 121 runs batted in. They have struck out on 171 occasions (9th in MLB) and have accounted for 188 hits. The Chicago Cubs have an on-base percentage of .340 in addition to a batting average of .255 on the campaign.
The Cubs are sitting with a team WHIP of 1.378 and have a FIP of 4.25 as a squad over the course of the season. They are currently ranked 30th in MLB as a pitching staff in total hits surrendered with 178. The Chicago pitching staff have surrendered 88 runs on the year while having a team ERA of 4.14 (85 earned runs relinquished). Their strikeout to walk ratio comes in at 7.70 (158 strikeouts vs 77 free passes). They have conceded 23 homers and they relinquish 4.28 runs per 9 innings (12th in the league).
Chicago relievers have an inherited score rate of 28.6% out of their 21 inherited runners. Their bullpen pitchers have come in 19 times in high leverage situations and on 15 occasions with base runners. Sitting with 24 save situations, the Cubs have compiled 13 holds and 5 blown saves. They rank 21st in baseball with a save rate of 54.5%, and they have dispatched 68 relief pitchers to the mound over the course of the season. Chicago has called on relievers to step onto the mound in 11 save opportunities and they have come away with 6 saves.
Out of their 1,665 innings on the diamond, the Cubs hold a efficiency on defense of 69.9% (21st in baseball). The Chicago Cubs have turned 14 double plays and have a fielding rate of .986 (13th in baseball). The Cubs have accrued 173 assists, 10 errors and have accounted for 555 putouts for the season.
In his pro baseball career, Taillon has conceded 1,093 base hits and he has 993 K's in 1,128 innings pitched. Taillon (72-54 record in his career) has earned a 3.92 ERA while giving up 8.7 hits per nine innings. He has allowed a total of 492 ER's while earning a WHIP of 1.210 and being the owner of a FIP of 3.9. He has a strikeout to walk ratio of 3.65 and he has faced 4,701 batters thus far in his career.
Who will win tonight's MLB game against the spread or moneyline?
Josh Schonwald's Pick: Take Chicago (+220)
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Additional Resources:
Chicago Cubs - Twitter
Arizona Diamondbacks - Twitter